ArticleMolecules (Basel, Switzerland)2026
Synthesis, Spectroscopy Characterization and Biological Evaluation of La(III), Eu(III) and Gd(III) Complexes with Ampicillin: In Vitro Antimicrobial, Cytotoxic and Antiproliferative Activities and Theoretical Frameworks.
Diego Boldo, Vasilii Khripun, Kristiane Fanti Del Pino, Juliana Jorge, Luana da Silva Oliveira, Danielle Bogo, Ana Camila Micheletti, Adriana Pereira Duarte, Hernane da Silva Barud, Ariadna Lafourcade Prada and 4 more
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In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
14 authors.
Diego BoldoChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0009-0004-5073-4632 Vasilii KhripunChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.
Kristiane Fanti Del PinoChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0000-0003-2162-5483 Juliana JorgeChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0000-0001-5755-9049 Luana da Silva OliveiraChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.
Danielle BogoFaculty of Pharmacy, Food and Nutrition, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0000-0003-0233-3047 Ana Camila MichelettiChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0000-0002-0797-6669 Adriana Pereira DuarteChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0000-0002-0335-8898 Hernane da Silva BarudLaboratory of Biopolymers and Biomaterials, University of Araraquara, Araraquara 14801-340, SP, Brazil.
Ariadna Lafourcade PradaFaculty of Pharmacy, Food and Nutrition, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.
Teofilo Fernando Mazon CardosoFaculty of Pharmacy, Food and Nutrition, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.ORCID 0000-0001-7392-7366 Gustavo Rocha de CastroInstitute of Biosciences, São Paulo State University, Botucatu 18618-689, SP, Brazil.ORCID 0000-0002-1218-2425 Jesus Rafael Rodríguez AmadoFaculty of Health Sciences, Federal University of Grande Dourados, Dourados 79825-070, MS, Brazil.ORCID 0000-0001-7574-6219 Marco Antonio Utrera MartinesChemistry Institute, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, MS, Brazil.
Funding
Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul 344/2022 694 (71/038.823/202259/300.074/2017)National Council for Scientific and Technological Development 311861/2023-7Universidade Federal de Mato Grosso do Sul Finance Code 001
6 · The paper itselfAbstract
This study reports the synthesis, characterization, DFT calculations and in vitro antimicrobial, cytotoxic and antiproliferative evaluation of La(III), Eu(III), and Gd(III) metal complexes with ampicillin. The compounds were characterized by Thermal Gravimetric Analysis (TGA), elemental analysis, ultraviolet-visible spectroscopy (UV-Vis), Fourier-transform infrared spectroscopy (FTIR), and proton nuclear magnetic resonance (
Indexed as
AmpicillinAnti-Infective AgentsAntineoplastic AgentsCoordination ComplexesEuropiumGadoliniumLanthanumAnimalsAnti-Bacterial AgentsCell Line, TumorCell ProliferationEscherichia coliHumansMiceMicrobial Sensitivity TestsStaphylococcus aureusAmpicillinAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsCoordination ComplexesEuropiumGadoliniumLanthanumampicillinantimicrobial activityDFT calculationslanthanides complexesspectroscopic studies
Identifiers
PMID42123829
PMCPMC13164664
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