Evidence map›Paper›PMID 42123653›Full record

ArticleInternational journal of molecular sciences2026

Intermittent Administration of Helminth-Derived Fh15 Modulates Gut Microbiota and Partially Mitigates Dysbiosis in Early Stages of Severe Experimental Colitis.

María Del Mar Figueroa-Gispert, Natalie M Meléndez-Vázquez, Ana M Espino, Filipa Godoy-Vitorino

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María Del Mar Figueroa-GispertDepartment of Microbiology and Immunology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.ORCID 0000-0002-7565-0193
Natalie M Meléndez-VázquezDepartment of Microbiology and Immunology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.ORCID 0000-0002-1538-7557
Ana M EspinoDepartment of Microbiology and Immunology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.ORCID 0000-0001-8456-2550
Filipa Godoy-VitorinoDepartment of Microbiology and Immunology, University of Puerto Rico-Medical Sciences Campus, San Juan, PR 00936, USA.ORCID 0000-0003-1880-0498

Funding

SCIENCE AND TECHNOLOGY COMPETENCY & EDUCATION CORE (STCE)P20GM103475 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Humberto Guillermo Ortiz-Zuazaga · 2012 to 2026
$52.9M
Upstream Regulation and Downstream effectors of c-MYC in Ovarian CancerU54MD007600 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Abiel Roche-Lima · 2017 to 2026
$35.8M
National Institutes of Health NIAID 1SC1AI155439-01National Institutes of Health NIGMS P20GM156713NIGMS NIH HHS P20 GM103475NIMHD NIH HHS U54 MD007600
6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by dysbiosis of the gut microbiota. Helminth infections are known to modulate host immunity and intestinal microbial composition; however, the therapeutic use of live parasites poses safety challenges. The recombinant

Indexed as

ColitisDysbiosisFasciola hepaticaGastrointestinal MicrobiomeHelminth ProteinsAnimalsDextran SulfateDisease Models, AnimalMaleMiceMice, Inbred C57BLRNA, Ribosomal, 16SDextran SulfateHelminth ProteinsRNA, Ribosomal, 16SDSSdysbiosisFasciola hepaticaFh15gut microbiotahelminthinflammatory bowel diseaseulcerative colitis

Identifiers

PMID42123653
PMCPMC13164252

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.