Evidence map›Paper›PMID 42123652›Full record

ArticleInternational journal of molecular sciences2026

Machine Learning-Driven QSAR Modeling for pK

Napat Kongtaworn, Borwornlak Toopradab, Duangjai Todsaporn, Poomrapee Tinpovong, Rada Thongsuebsaeng, Phornphimon Maitarad, Thanyada Rungrotmongkol

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Napat KongtawornProgram in Bioinformatics and Computational Biology, College of Interdisciplinary and Integrative Studies, Chulalongkorn University, Bangkok 10330, Thailand.
Borwornlak ToopradabProgram in Bioinformatics and Computational Biology, College of Interdisciplinary and Integrative Studies, Chulalongkorn University, Bangkok 10330, Thailand.
Duangjai TodsapornCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Poomrapee TinpovongProgram in Bioinformatics and Computational Biology, College of Interdisciplinary and Integrative Studies, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0009-0005-3252-6415
Rada ThongsuebsaengCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Phornphimon MaitaradCenter of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-0035-0070
Thanyada RungrotmongkolProgram in Bioinformatics and Computational Biology, College of Interdisciplinary and Integrative Studies, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-7402-3235

Funding

90th Anniversary of Chulalongkorn University Fund GCUGR1125671132DHigh-Performance Computing Center of Shanghai University and the Shanghai Engineering Re-search Center of Intelligent Computing System 19DZ2252600NSRF via the Program Management Unit for Human Resources & Institutional Development, Research and Innovation B38G680006Second Century Fund (C2F), Chulalongkorn University, for a PhD scholarship
6 · The paper itself

Abstract

Liver cancer remains a significant global health burden, requiring the development of precise nucleic acid delivery systems. Lipid nanoparticles (LNPs) are leading candidates; however, their efficiency is governed by the pK

Indexed as

Gene SilencingLipidsLiverMachine LearningNanoparticlesQuantitative Structure-Activity RelationshipBoosting Machine Learning AlgorithmsHumansLiposomesPrediction AlgorithmsPredictive Learning ModelsRandom ForestLipid NanoparticlesLipidsLiposomesgene silencingionizable lipid designlipid nanoparticlesmachine learning QSARpKa prediction

Identifiers

PMID42123652
PMCPMC13164459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.