Evidence map›Paper›PMID 42123627›Full record

ArticleInternational journal of molecular sciences2026

Sex-Specific Patterns of Taste Dysfunction, Their Relationships with α-Synuclein Profiling, and Supervised Learning-Based Diagnosis in Parkinson's Disease (PD).

Melania Melis, Fabrizio Angius, Lala Chaimae Naciri, Giorgia Sollai, Silvia Deligia, Giuseppe Fenu, Paolo Mellino, Beatrice Pinna, Roberto Crnjar, Anna R Carta and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Melania MelisDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0003-3410-3158
Fabrizio AngiusDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0001-6613-603X
Lala Chaimae NaciriDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.
Giorgia SollaiDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0001-7341-582X
Silvia DeligiaDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.
Giuseppe FenuDepartment of Neurology, AO Brotzu, 09134 Cagliari, Italy.
Paolo MellinoDepartment of Neurology, AO Brotzu, 09134 Cagliari, Italy.
Beatrice PinnaDepartment of Neurology, AO Brotzu, 09134 Cagliari, Italy.ORCID 0009-0003-8769-8965
Roberto CrnjarDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.
Anna R CartaDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0003-3104-9010
Giovanni CossuDepartment of Neurology, AO Brotzu, 09134 Cagliari, Italy.
Iole Tomassini BarbarossaDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-2849-4052

Funding

MNESYS European Union, Next Generation EU, Missione 4 Componente 2 investimento 1.3 B33C22001060002UniCA - Progetti di Ricerca Start-Up D.M. 737/2021- Linea d'intervento Iniziative di ricerca in-terdisciplinare sui temi di rilievo trasversale per il PNR, finanziato dall'Unione europea - Next Generation EU F25F21002720001
6 · The paper itself

Abstract

Taste impairment is a little-known non-motor Parkinson's disease (PD) feature with potential diagnostic value. However, its biological basis and sex-specific patterns remain unclear. We combined psychophysical taste testing, salivary α synuclein (αsyn) profiling, genotyping of four

Indexed as

alpha-SynucleinParkinson DiseaseTaste DisordersAgedFemaleGenotypeHumansMaleMiddle AgedPolymorphism, Single NucleotideSalivaSex FactorsSupervised Machine LearningTastealpha-SynucleinSNCA protein, humansalivary oligomeric α-synsupervised learningtaste perceptionα-synuclein genetic variants

Identifiers

PMID42123627
PMCPMC13164297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.