Evidence map›Paper›PMID 42123581›Full record

ArticleInternational journal of molecular sciences2026

A Rare CTBP1-Related Neurodevelopmental Disorder Is Associated with Impaired Mitochondrial Bioenergetics: A Functional Case Report.

Zdravko Ivanov, Maria Gevezova, Iliyana Pacheva, Kostadin Ketev, Lyubov Chochkova-Bukova, Victoria Sarafian, Ivan Ivanov

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Delineating theInternational journal of molecular sciences · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zdravko IvanovPediatrics Clinic, St. George University Hospital, 4002 Plovdiv, Bulgaria.ORCID 0009-0004-2659-9696
Maria GevezovaDepartment of Medical Biology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Iliyana PachevaPediatrics Clinic, St. George University Hospital, 4002 Plovdiv, Bulgaria.
Kostadin KetevPediatrics Clinic, St. George University Hospital, 4002 Plovdiv, Bulgaria.ORCID 0000-0001-5395-9125
Lyubov Chochkova-BukovaPediatrics Clinic, St. George University Hospital, 4002 Plovdiv, Bulgaria.
Victoria SarafianDepartment of Medical Biology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-1501-0175
Ivan IvanovPediatrics Clinic, St. George University Hospital, 4002 Plovdiv, Bulgaria.

Funding

European Union-NextGenerationEU No BG-RRP-2.004- 0007-C03
6 · The paper itself

Abstract

The C-terminal binding protein 1 (CTBP1) is a transcriptional corepressor with a major role in nervous system growth and development. There are only 20 published cases with

Indexed as

Alcohol OxidoreductasesDNA-Binding ProteinsEnergy MetabolismMitochondriaNeurodevelopmental DisordersChildFemaleHumansMutationAlcohol OxidoreductasesC-terminal binding proteinDNA-Binding ProteinsCTBP1 mutationHADDTSmitochondrial dysfunctionmitochondria-targeted nutritional supplementationMito Stress TestSeahorse

Identifiers

PMID42123581
PMCPMC13163389

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.