Evidence map›Paper›PMID 42123493›Full record

ArticleInternational journal of molecular sciences2026

Tumor Suppressor CADM1 Protects Against Colitis in Inflammatory Bowel Disease Through Enhancing Epithelial Regeneration.

Yuki Hanaoka-Ikeda, Yumi Tsuboi, Yutaka Kasai, Tomoko Masuda, Hiromi Ichihara, Sumiko Watanabe, Masaru Shinozaki, Yasunori Ohta, Daisuke Matsubara, Yoshinori Murakami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuki Hanaoka-IkedaDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Yumi TsuboiDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Yutaka KasaiDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.ORCID 0009-0007-4372-6468
Tomoko MasudaDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Hiromi IchiharaDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Sumiko WatanabeDivision of Molecular and Developmental Biology, Institute of Medical Science, The University of Tokyo, Tokyo 113-8639, Japan.
Masaru ShinozakiDepartment of Surgery, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
Yasunori OhtaDepartment of Laboratory Medicine, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.
Daisuke MatsubaraDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Yoshinori MurakamiDivision of Molecular Pathology, Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

Funding

Japan Agency for Medical Research and Development 25ama221352, 20ck0106424, 19ae0101073, 16cm0106416Japan Society for the Promotion of Science 23790391Japan Society for the Promotion of Science 24K02319, 22H04923, 20K21539, 20H03525, 25290051
6 · The paper itself

Abstract

Dysregulation of the immune system, gut microbiota alteration, and epithelial dynamics in the colon contribute to the pathogenesis of inflammatory bowel disease (IBD). However, the role of epithelial dynamics, particularly epithelial regeneration, remains incompletely understood.

Indexed as

Cell Adhesion Molecule-1ColitisInflammatory Bowel DiseasesIntestinal MucosaRegenerationAnimalsApoptosisbeta CateninColonDextran SulfateDisease Models, AnimalEpithelial CellsHumansIntestinal Barrier FunctionMiceMice, Inbred C57BLbeta CateninCADM1 protein, humanCadm1 protein, mouseCell Adhesion Molecule-1Dextran SulfateProto-Oncogene Proteins c-aktCADM1dextran sulfate sodiumepithelial regenerationhuman inflammatory bowel diseaseβ-catenin

Identifiers

PMID42123493
PMCPMC13164419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.