Evidence map›Paper›PMID 42123481›Full record

ArticleInternational journal of molecular sciences2026

Relative Leukocyte Telomere Length Is Shorter in Children and Adolescents with Type 1 Diabetes: Screening of Basic Psychosocial Aspects.

Georgia Papavasileiou, Eleni Dragona, Nicolas C Nicolaides, Tania Siahanidou, Maria Michou, Emmanouil Zoumakis, Sarantis Gagos, Christina Kanaka-Gantenbein

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Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Georgia PapavasileiouPost-Graduate Course of Stress Science and Health Promotion, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0009-0003-0267-0892
Eleni DragonaLaboratory of Genetics, Centre of Experimental Medicine and Translational Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.ORCID 0009-0006-8019-6729
Nicolas C NicolaidesPost-Graduate Course of Stress Science and Health Promotion, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-8260-1309
Tania SiahanidouPost-Graduate Course of Stress Science and Health Promotion, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-8991-0649
Maria MichouPost-Graduate Course of Stress Science and Health Promotion, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Emmanouil ZoumakisPost-Graduate Course of Stress Science and Health Promotion, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-5234-0742
Sarantis GagosLaboratory of Genetics, Centre of Experimental Medicine and Translational Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.ORCID 0000-0003-4907-7706
Christina Kanaka-GantenbeinPost-Graduate Course of Stress Science and Health Promotion, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-6942-6470

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukocyte telomere length (LTL) is shortened in adults with type 1 diabetes (T1D), but less data is available concerning pediatric cases. Multiple factors affect LTL, namely genes, epigenetics, environmental factors, oxidation, and psychological stress. Children with T1D and their families experience chronic stress. This study aimed to investigate LTL in children with T1D (n = 35) aged 6-13 years old, in comparison to age-matched healthy counterparts (n = 35), and assess any correlation of LTL with perceived stress. Relative LTL (rLTL) was assessed through real-time qPCR. Morning serum cortisol, high-sensitivity C-Reactive Protein (hsCRP), and glycated hemoglobin (HbA1c) were measured. Children completed the validated questionnaires "Stress in Children" and "Pediatric Quality of Life". Parents answered the "Perceived Stress Scale". Children with T1D had a lower rLTL (

Indexed as

Diabetes Mellitus, Type 1LeukocytesTelomereTelomere ShorteningAdolescentCase-Control StudiesChildC-Reactive ProteinFemaleGlycated HemoglobinHumansMaleQuality of LifeStress, PsychologicalC-Reactive ProteinGlycated Hemoglobinchildrenleukocyte telomere lengthperceived social supportstresstype 1 diabetes

Identifiers

PMID42123481
PMCPMC13164480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.