Evidence map›Paper›PMID 42123461›Full record

ArticleInternational journal of molecular sciences2026

Molecular Characterization of Omega-3 Fatty Acid Desaturases Reveals Functional Conservation and Their Pivotal Role in Salt and Temperature Stress Adaptation in

Sajeel Hussain, Ye-Song Kim, Ashim Kumar Das, Da-Sol Lee, Adil Hussain, Byung-Wook Yun

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sajeel HussainDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0009-0004-0296-3246
Ye-Song KimDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0009-0003-4468-6497
Ashim Kumar DasDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0001-6012-4812
Da-Sol LeeDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0009-0005-7045-4619
Adil HussainDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-7803-429X
Byung-Wook YunDepartment of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.ORCID 0000-0002-5451-2365

Funding

Korea Basic Science Institute 2021R1A6C101A416Ministry of Education 2025-RISE-03-001National Research Foundation of Korea RS-2023-00245922
6 · The paper itself

Abstract

Omega-3 fatty acid desaturases (FAD3, FAD7, and FAD8) are key enzymes responsible for the production of α-linolenic acid (ALA), which is an essential polyunsaturated fatty acid regulating membrane stability and serves as a precursor for jasmonic acid. In this study, we performed a comprehensive genome-wide molecular characterization of omega-3 fatty acid desaturase genes across seven plant species. Phylogenetic analysis placed FAD3 and FAD7/FAD8 proteins in distinct clades, indicating functional divergence despite strong sequence conservation. Gene structure analysis revealed conserved exon-intron formation with a few unique features. Multiple sequence alignment and motif analysis revealed high sequence similarity with three histidine-rich boxes responsible for catalytic activity.

Indexed as

Adaptation, PhysiologicalArabidopsisArabidopsis ProteinsFatty Acid DesaturasesSalt StressStress, PhysiologicalGene Expression Regulation, PlantPhylogenyArabidopsis Proteinsfad3 protein, ArabidopsisFad7 protein, ArabidopsisFatty Acid Desaturasesomega-3 fatty acid desaturasechloroplastendoplasmic reticulumin silico analysisomega-3 fatty acid desaturasesalt stress and temperature

Identifiers

PMID42123461
PMCPMC13164332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.