Evidence map›Paper›PMID 42123451›Full record

ArticleInternational journal of molecular sciences2026

An Exploratory LC-HRMS Metabolomics Study of Culture Medium-Dependent Metabolic Variation and Bioactivity in Ten Fungal Strains.

Ria Desai, Gagan Preet, Rishi V Astakala, Adriana Romero-Otero, Pilar Sanchez, Thomas A Mackenzie, Thomas O Larsen, Rainer Ebel, Marcel Jaspars

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ria DesaiMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0009-0000-3997-7570
Gagan PreetMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0000-0002-7978-7306
Rishi V AstakalaMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.
Adriana Romero-OteroDepartment of Biotechnology and Biomedicine, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.ORCID 0000-0002-2558-647X
Pilar SanchezFundación MEDINA, Avda Conocimiento 34, 18016 Granada, Spain.
Thomas A MackenzieFundación MEDINA, Avda Conocimiento 34, 18016 Granada, Spain.ORCID 0009-0000-4297-6966
Thomas O LarsenDepartment of Biotechnology and Biomedicine, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
Rainer EbelMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0000-0002-9702-2235
Marcel JasparsMarine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.ORCID 0000-0002-2426-6028

Funding

Biotechnology and Biological Sciences Research Council BBSRC ALERT-22 Grant BB/X019802/1UK Research and Innovation HOTBIO (RG16804-10)
6 · The paper itself

Abstract

Fungi represent a prolific source of structurally diverse secondary metabolites, yet the extent to which culture conditions reshape the metabolic profile and functional bioactivity remains incompletely understood. In this exploratory study, ten fungal strains belonging to genera

Indexed as

AspergillusCulture MediaFungiMetabolomeMetabolomicsPenicilliumChromatography, LiquidLiquid Chromatography-Mass SpectrometryTerpenesCulture MediaTerpenescytotoxic activityfungal secondary metabolismmetabolite-bioactivity associationmolecular networkingOPLS regressionuntargeted metabolomics

Identifiers

PMID42123451
PMCPMC13163426

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.