Evidence map›Paper›PMID 42123443›Full record

ArticleInternational journal of molecular sciences2026

Effect of Sertraline on Fetoplacental Growth Parameters and Placental Transporter Gene Expression in Rats.

Daniel Enriquez-Mendiola, Jorge E Sifuentes-García, Laura J Barragán-Zúñiga, Angel A Vértiz-Hernández, Blanca P Lazalde-Ramos, Alicia E Damiano, Carlos Galaviz-Hernández, Martha Sosa-Macías

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel Enriquez-MendiolaGenomics Academy, CIIDIR-Durango, Instituto Politécnico Nacional, Durango 34220, Mexico.ORCID 0000-0001-8411-8871
Jorge E Sifuentes-GarcíaGenomics Academy, CIIDIR-Durango, Instituto Politécnico Nacional, Durango 34220, Mexico.
Laura J Barragán-ZúñigaCentro Estatal de Cancerología, Secretaria de Salud de Durango, Durango 34000, Mexico.ORCID 0000-0002-9925-6668
Angel A Vértiz-HernándezUnidad Académica Regional Altiplano, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78600, Mexico.ORCID 0000-0002-7555-8303
Blanca P Lazalde-RamosMaestría en Ciencia y Tecnología Química, Unidad Académica de Ciencias Químicas, Universidad Autónoma de Zacatecas, Zacatecas 98160, Mexico.
Alicia E DamianoDepartamento de Ciencias Biológicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires C1113AAD, Argentina.
Carlos Galaviz-HernándezGenomics Academy, CIIDIR-Durango, Instituto Politécnico Nacional, Durango 34220, Mexico.
Martha Sosa-MacíasGenomics Academy, CIIDIR-Durango, Instituto Politécnico Nacional, Durango 34220, Mexico.

Funding

Instituto Politécnico Nacional SIP 20250970 / 20250979
6 · The paper itself

Abstract

The aim of this study was to assess the effect of sertraline on the gene expression of placental transporters for hormones, folates, nutrients and drugs over the course of pregnancy in rats. The studies were conducted on gestational days (GDs) 16 and 20 following oral treatment with 10 mg/kg/day sertraline or the vehicle, administered from weaning onward. The weight and area of the fetuses and placentas were analyzed, and maternal plasma sertraline concentrations were measured. Gene expression of ATP-binding cassette transporter b1a and b1b (

Indexed as

Fetal DevelopmentPlacentaSertralineAnimalsFemaleGene Expression Regulation, DevelopmentalPregnancyRatsSertralinedrug transporterfetal developmentnutrient transporterplacental efficiencySSRI

Identifiers

PMID42123443
PMCPMC13164233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.