ArticleInternational journal of molecular sciences2026
Extracellular Vesicle from
Hinata Harada, Yusuke Ohsaki, Afifah Zahra Agista, Hsin-Jung Ho, Takuo Hirose, Kotaro Yamada, Mutsumi Furukawa, Tomonori Nochi, Wan-Chun Chiu, Ya-Ling Chen and 4 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Hinata HaradaLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Yusuke OhsakiLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Afifah Zahra AgistaLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Hsin-Jung HoLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0001-8421-4919 Takuo HiroseDivision of Physiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai 983-8536, Japan.ORCID 0000-0002-8761-3779 Kotaro YamadaRegulatory Affairs Promotion Division, ROHTO Pharmaceutical Co., Ltd., Osaka 544-8666, Japan.
Mutsumi FurukawaInternational Education and Research Center for Food Agricultural Immunology, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.
Tomonori NochiInternational Education and Research Center for Food Agricultural Immunology, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0003-1800-6972 Wan-Chun ChiuSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0003-4638-5412 Ya-Ling ChenSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.
Chiu-Li YehSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-8245-4601 Suh-Ching YangSchool of Nutrition and Health Sciences, College of Nutrition, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-1579-2165 Takefumi MoriDivision of Nephrology and Hypertension, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai 983-8536, Japan.
Hitoshi ShirakawaLaboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai 980-8572, Japan.ORCID 0000-0002-4828-5274 Funding
Rohto Pharmaceutical (Japan) N/ATohoku University N/A
6 · The paper itselfAbstract
Metabolic-dysfunction-associated steatotic liver disease (MASLD) is a major chronic liver disorder that progresses through inflammation and fibrosis to cirrhosis, yet no effective pharmacological therapy is available. Extracellular vesicles (EVs), which are key mediators of intercellular communication, have recently been reported to exert preventative and therapeutic effects in disease models. This study evaluated the oral efficacy of EVs derived from the microalga
Indexed as
Chlorella vulgarisExtracellular VesiclesFatty LiverInflammationLiver CirrhosisAnimalsDiet, High-FatDisease Models, AnimalLiverMaleMiceMice, Inbred C57BLSignal TransductionChlorella vulgarisexosomeextracellular vesicleshepatic fibrosishepatic steatosisinflammationKupffer cellliver diseasemacrophageMASLDmicroalgae
Identifiers
PMID42123321
PMCPMC13163729
What OpenQuestion holds
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LicenceCC BY
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