Evidence map›Paper›PMID 42122728›Full record

ReviewPolymers2026

Exploring the Versatility and Sustainability of Hydroxypropyl Methylcellulose (HPMC) in Modern Chemical Industry.

Sonia Matilla, Ackmez Mudhoo, Carlos Díez, Marta Otero

Abstract readReview
In one paragraph

Review in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sonia MatillaDepartmento de Química y Física Aplicadas, Universidad de León, Campus de Vegazana, 24071 León, Spain.
Ackmez MudhooDepartment of Chemical and Environmental Engineering, Faculty of Engineering, University of Mauritius, Réduit 80837, Mauritius.ORCID 0000-0001-5712-6673
Carlos DíezLaboratorios León Farma, S.A., Insud Farma, C/La Vallina, Navatejera, 24193 León, Spain.
Marta OteroDepartmento de Química y Física Aplicadas, Universidad de León, Campus de Vegazana, 24071 León, Spain.ORCID 0000-0001-5218-0726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxypropyl methylcellulose (HPMC) is a cellulose derivative characterized by physicochemical properties (gel formation, water solubility, biodegradability, and biocompatibility). These properties explain their wide use in industries such as pharmaceuticals, food, and construction. This review evaluates the classification, production processes, and analytical characterization of HPMC, with particular attention to its versatility and sustainability life cycle. The environmental impact of HPMC is analyzed through its energy-intensive production, waste generation, emissions, and end-of-life biodegradability. In comparison with many petroleum-based polymers, HPMC is often considered a greener option and its use as an additive in modern chemical industry is extended. Therefore, the adoption of more sustainable production practices is essential to minimize its ecological footprint. In this sense, greener raw material sourcing, improved production process efficiency, lower emission etherification and purification routes, and broader implementation of life-cycle-based optimization strategies were identified as key priorities to be addressed.

Indexed as

biodegradable polymerscellulose derivativesgreen chemistrysustainabilitythermogelable polymers

Identifiers

PMID42122728
PMCPMC13165829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.