Evidence map›Paper›PMID 42122715›Full record

ReviewPolymers2026

Bioplastics Toxicity upon Ingestion: A Critical Review of Biotransformation and Gastrointestinal Effects.

Cristiana Fernandes, Helena Oliveira, Teresa Rocha-Santos, Verónica Bastos

Abstract readReview
In one paragraph

Review in Polymers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristiana FernandesCentre for Environmental and Marine Studies (CESAM), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0009-0003-1512-4831
Helena OliveiraCentre for Environmental and Marine Studies (CESAM), Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-4673-0696
Teresa Rocha-SantosCentre for Environmental and Marine Studies (CESAM), Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-3660-4116
Verónica BastosCentre for Environmental and Marine Studies (CESAM), Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0002-9882-4766

Funding

Foundation for Science and Technolog 10.54499/2022.05740.CEECIND/CP1720/CT0031Foundation for Science and Technology 10.54499/CEECIND/04050/2017/CP1459/CT0023Foundation for Science and Technology COMPETE2030-FEDER-00843100Foundation for Science and Technology UID/50006 + LA/P/0094/2020
6 · The paper itself

Abstract

In response to the plastic pollution crisis, bioplastics emerged as a sustainable alternative. However, low degradation rate and abiotic decomposition generate micro- and nanoplastics. These particles enter the food chain, establishing oral intake as a key route of human exposure. This review gathered studies on the biotransformation of bioplastics in the gastrointestinal tract and on their toxicity in human cells and murine models. Most studies focused on polylactic acid particles due to widespread use in food packaging. Under simulated gastrointestinal conditions in vitro, particles were modulated, resulting in cavity and pore formation, fragmentation, lipase competition, protein corona formation, and alterations in the gut microbiota (including

Indexed as

bioplasticcytotoxicitygastrointestinal tracthuman healthinflammationmicro- and nanoplasticsoxidative stress

Identifiers

PMID42122715
PMCPMC13165661

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.