Evidence map›Paper›PMID 42122200›Full record

ReviewCancers2026

Health Impacts of Chronic Radiation Exposure in Northern Kazakhstan: A Comprehensive Epidemiological Review.

Polat Kazymbet, Kuralay Ilbekova, Elena Saifulina, Mulkat Yelshenbek, Yerlan Kashkinbayev, Danara Ibrayeva, Moldir Aumalikova, Dinara Bizhanova, Yerbol Dogalbayev, Meirat Bakhtin

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Polat KazymbetScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Kuralay IlbekovaScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Elena SaifulinaScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.ORCID 0000-0002-1791-0137
Mulkat YelshenbekScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Yerlan KashkinbayevScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Danara IbrayevaScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Moldir AumalikovaScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.
Dinara BizhanovaScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.ORCID 0000-0001-8172-768X
Yerbol DogalbayevDepartment of Interventional Radiology, CF University Medical Center, Astana 010000, Kazakhstan.ORCID 0000-0001-8239-563X
Meirat BakhtinScientific Research Institute of Radiobiology and Radiation Protection, NJSC "Astana Medical University", Astana 010000, Kazakhstan.

Funding

Science Committee of the Ministry of Education and Science of the Republic of Ka-zakhstan AP26194983
6 · The paper itself

Abstract

Chronic exposure to ionizing radiation from uranium legacy sites remains a significant public health concern in Northern Kazakhstan. This review evaluates epidemiological, clinical, and environmental evidence published between 2000 and 2025, with particular emphasis on studies conducted during 2014-2023 in the Stepnogorsk region among populations residing near former uranium mining sites. Residents were exposed to annual external gamma doses of approximately 1.0-3.5 mSv and radon-related doses of up to 1.2 mSv. Cancer registry analyses revealed 1913 malignancy cases in the exposed group (vs. 358 controls), with digestive (29%) and respiratory (17%) cancers predominating. Early signs of chronic radiation syndrome (CRS) were consistently observed, including olfactory dysfunction, immunosuppression, vestibular disturbances, hematologic anomalies, and elevated chromosomal aberrations (1.3-1.5× baseline). Non-cancer morbidity was also elevated, including hypertension (32% vs. 24%), chronic bronchitis (14% vs. 8%), and reduced forced expiratory volume in one second (FEV

Indexed as

cancer riskchronic radiation syndromeenvironmental healthformer uranium mining sitesradon exposure

Identifiers

PMID42122200
PMCPMC13162763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.