Evidence map›Paper›PMID 42122158›Full record

ArticleCancers2026

Genome-Scale CRISPR Screens Reveal DNA Repair Dependencies That Sensitize Hepatocellular Carcinoma to Oxaliplatin.

Hanyue Ouyang, Diyun Huang, Dongsheng Wen, Lichang Huang, Zichao Wu, Zhicheng Lai, Minke He, Wenchao Wu, Ming Shi

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hanyue OuyangDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Diyun HuangDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0009-0007-4660-6090
Dongsheng WenDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Lichang HuangDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Zichao WuDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Zhicheng LaiDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Minke HeDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
Wenchao WuDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.ORCID 0000-0002-6035-3233
Ming ShiDepartment of Hepatobiliary Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

Funding

China Postdoctoral Science Foundation No. 2023TQ0390National Key Research and Development Program of China No. 2023YFA0915703National Natural Science Foundation of China No. 82203126National Natural Science Foundation of China No. 82272890Young Talents Program of Sun Yat-sen University Cancer Center YTP-SYSUCC-0071 and YTP-SYSUCC-0077
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRISPR-Cas9 screenDNA repairhepatocellular carcinomaoxaliplatin

Identifiers

PMID42122158
PMCPMC13162874

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.