Evidence map›Paper›PMID 42122123›Full record

ReviewCancers2026

Clonal Hematopoiesis of Indeterminate Potential (CHIP): A Model of Mutation-Driven Thromboinflammation.

Bouse Malkots, Iliana Stamatiou, Emmanuil Panagiotopoulos, Lydia Inglezou, Vasiliki Sakka, Georgios Vrachiolias, Christina Misidou, Emmanuil Spanoudakis, Ioannis Kotsianidis, Konstantinos Liapis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bouse MalkotsDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0009-0007-0156-9484
Iliana StamatiouDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0009-0007-6458-8201
Emmanuil PanagiotopoulosDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.
Lydia InglezouDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0000-0002-5302-4511
Vasiliki SakkaDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.
Georgios VrachioliasDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0000-0003-1705-0146
Christina MisidouDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0000-0002-7771-7419
Emmanuil SpanoudakisDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0000-0003-4985-5862
Ioannis KotsianidisDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0000-0001-7668-0186
Konstantinos LiapisDepartment of Hematology, Democritus University of Thrace, 68 100 Alexandroupolis, Greece.ORCID 0000-0003-1165-9639

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clonal hematopoiesis refers to the clonal expansion of hematopoietic stem and progenitor cells, driven by somatic mutations. Major mutated genes in clonal hematopoiesis include genes involved in epigenetic regulation including DNA methylation and/or chromatin modification (e.g.,

Indexed as

atherosclerosiscardiovascular diseaseCHIPclonal hematopoiesisimmunothrombosisinflammaginginflammationMDSmyelodysplastic syndromesomatic mutationsthromboembolismthromboinflammationthrombosis

Identifiers

PMID42122123
PMCPMC13162574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.