Evidence map›Paper›PMID 42121646›Full record

ArticleHealthcare (Basel, Switzerland)2026

Quality of Life and Functional Outcomes After Rectal Cancer Surgery: A Comparative Study Applying EORTC QLQ-C30, QLQ-CR29, and LARS Score at 1-6 Months Postoperatively.

Floris Cristian Stanculea, Claudiu O Ungureanu, Octav Ginghina, Razvan A Stoica, Raul Mihailov, Valerii Lutenco, Valentin T Grigorean, Mircea Litescu, Niculae Iordache

Abstract read
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Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Floris Cristian StanculeaGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0005-5366-5684
Claudiu O UngureanuGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0009-8176-0434
Octav GinghinaGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Razvan A StoicaGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Raul MihailovGeneral Surgery Department, "Sf. Andrei" Clinical Emergency Hospital, 177 Braila Street, 800578 Galati, Romania.ORCID 0000-0001-7081-9490
Valerii LutencoGeneral Surgery Department, "Sf. Andrei" Clinical Emergency Hospital, 177 Braila Street, 800578 Galati, Romania.ORCID 0009-0001-6620-7851
Valentin T GrigoreanGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mircea LitescuGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-6022-2236
Niculae IordacheGeneral Medicine Faculty, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0009-0005-4068-7577

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesQuality of life (QoL) and functional recovery are essential outcomes in patients undergoing rectal cancer surgery. In addition to oncological results, bowel dysfunction and stoma-related issues may significantly affect postoperative well-being. We aimed to evaluate QoL changes at 1 and 6 months postoperatively and functional outcomes in rectal cancer patients who underwent curative surgical treatment, sphincter-preserving surgeries (SPS) or abdominoperineal resection (APR). Owing to its impact on QoL, several functions were assessed using the Low Anterior Resection Syndrome (LARS) score.

methodsThis retrospective observational study consisted of 99 patients who underwent curative rectal cancer surgery, of which 38 patients had colostomy, and 61 no colostomy. To assess patient-reported outcomes related to QoL, the EORTC QLQ-C30 questionnaire, QLQ-CR29 questionnaire, and LARS instrument were sent to the patients at 1 and 6 months postoperatively. Changes over time were analyzed using paired statistical tests, and subgroup analyses were performed according to colostomy status and surgical approach.

resultsSignificant improvements were observed in the global health status and all major functional domains between 1 and 6 months postoperatively. The global health status increased from 74.9% to 86.5% (

conclusionsIn this study, QoL and bowel function improved significantly during the first 6 months after colorectal cancer surgery. Although most patients demonstrated recovery, persistent bowel dysfunction and stoma-related challenges remain important issues. These findings highlight the need for comprehensive postoperative care and routine assessment of both QoL and functional outcomes.

Indexed as

colostomyEORTC QLQ-C30EORTC QLQ-CR29LARSpostoperative outcomesPROMquality of liferectal cancer

Identifiers

PMID42121646
PMCPMC13163284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.