Hawthorn Polysaccharides Relieve High-Fat Blood Disease in Mice by Improving Intestinal Flora and Promoting Lipid Metabolism.

Jingxuan Ke, Xinyu Li, Xiaoyu Yin, Yabin Wang, Xin Wang, Qingshan Shen, Yanli Ma

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Jingxuan KeZhang Zhongjing College of Health Preservation and Food Science, Nanyang Institute of Technology, Nanyang 473004, China.

Xinyu LiZhang Zhongjing College of Health Preservation and Food Science, Nanyang Institute of Technology, Nanyang 473004, China.

Xiaoyu YinZhang Zhongjing College of Health Preservation and Food Science, Nanyang Institute of Technology, Nanyang 473004, China.

Yabin WangZhang Zhongjing College of Health Preservation and Food Science, Nanyang Institute of Technology, Nanyang 473004, China.

Xin WangCollege of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China.

Qingshan ShenZhang Zhongjing College of Health Preservation and Food Science, Nanyang Institute of Technology, Nanyang 473004, China.

Yanli MaZhang Zhongjing College of Health Preservation and Food Science, Nanyang Institute of Technology, Nanyang 473004, China.ORCID 0000-0002-2588-5007

Funding

Natural Science Foundation Project of Henan Province 252300420708Natural Science Foundation Project of Henan Province 262300422154

6 · The paper itself

Abstract

In this research, the anti-hyperlipidemic effects of hawthorn polysaccharides in experimental mice fed a high-fat diet were thoroughly investigated. The findings indicated that the body and organ weights of the high-fat group (HC) mice increased significantly, fat accumulation was evident, and serum indicators showed elevated lipid levels. After 8 weeks of the intragastric administration of hawthorn polysaccharides, the data showed that the body weight of the hawthorn polysaccharide (HA) group was notably lower than that of the HC group and close to that of the NC group. In addition, the hawthorn polysaccharide intervention improved the symptoms of the mice. In particular, the hawthorn polysaccharide intervention significantly increased HDL-C levels and decreased LDL-C levels in the HA group mice. Furthermore, gut microbiota analysis demonstrated that a high-fat diet altered its structure. The intervention with hawthorn polysaccharides modulated the intestinal flora structure, lowered the F/B ratio, and increased the abundance of beneficial bacterial strains associated with lower blood lipid levels.

Indexed as

alleviate hyperlipidemiahawthorn polysaccharideshigh-fat dietlipid metabolism

Identifiers

PMID42121468

DOI10.3390/foods15091525

PMCPMC13163799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.