ArticleJournal of cosmetic dermatology2026
Safety and Tolerability of Fractional CO
Article in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFractional CO
methodsWe conducted a single-center retrospective study of 38 patients (Fitzpatrick skin phototypes I-IV) treated with fractional CO
resultsMean pain score was 4.8, with no statistically significant difference between patients who received topical anesthetic (LMX4) and those who did not. Pain scores did not differ significantly across skin phototypes I-IV. Erythema occurred in 50% of patients and edema in 24%, all of which were transient. No cases of blistering, post-inflammatory hyperpigmentation, or scarring were documented in routine clinical records, although the true incidence may be underestimated. Erythema rates did not differ significantly by anesthetic use.
conclusionsIn this preliminary cohort, the HP fractional laser was associated with transient short-term adverse effects and no documented pigmentary complications among patients with Fitzpatrick skin types I-IV. These findings are descriptive and are not generalizable to Fitzpatrick phototypes V-VI, which were not represented.
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