ArticleMedical physics2026
Advancing iris melanoma brachytherapy: Eye plaque models for Monte Carlo simulations and 3D dosimetric datasets.
Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo develop and benchmark eye plaque models for Monte Carlo (MC) simulation of iris melanoma brachytherapy and to develop a database of 3D dose distributions for the iris plaques containing ACQUISITION AND VALIDATION
methodsFive iris plaque models are developed with egs_brachy using published dimensions and material data; previously benchmarked seed models are used. Three plaque models are based on those used by the Mayo Clinic, consisting of a modification of the COMS 22 mm plaque design with a 10 mm void in the center surrounded by an inner collimating lip; plaques span DATA FORMAT AND USAGE NOTES: The eye plaque models will be distributed with egs_brachy on GitHub (https://github.com/clrp-code/egs_brachy), along with an input file to facilitate custom simulations. The dosimetric database (https://doi.org/10.5281/zenodo.14776641) is comprised of 3D dose distributions for each plaque type, simulation condition, and radionuclides. POTENTIAL APPLICATIONS: The iris plaque models enable custom simulations with the open-access egs_brachy code. The database of 3D dose distributions supports advanced dose evaluations, as recommended by AAPM Task Group 221 on Ocular Brachytherapy. Overall, this work supports adoption of model-based dose evaluations for brachytherapy as recommended by TG-186.
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