Evidence map›Paper›PMID 42120929›Full record

ArticleLeukemia2026

Comprehensive mutational profiling and clinical outcome of adult acute myeloid leukemia patients with NUP98 rearrangement.

Benoit Ducourneau, Arnaud Pages, Stéphanie Struski, Matthieu Decamp, Emmanuel Raffoux, Céline Berthon, Laurène Fenwarth, Vincent Marmouset, Cécile Pautas, Thomas Cluzeau and 31 more

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Article in Leukemia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Benoit DucourneauLaboratory of Hematology, Lille University Hospital, Lille, France.
Arnaud PagesDepartment of Biostatistics, Gustave Roussy, Villejuif, France.ORCID http://orcid.org/0000-0002-2337-8693
Stéphanie StruskiCentre Hospitalo-universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Université de Toulouse, Toulouse, France.
Matthieu DecampDepartment of Cytogenetics, University Hospital of Caen, Caen, France.
Emmanuel RaffouxDepartment of Hematology, Hôpital Saint Louis, Assistance publique Hôpitaux de Paris and Paris University, Paris, France.ORCID http://orcid.org/0000-0003-3925-7391
Céline BerthonDepartment of Hematology, Lille University Hospital, Lille, France.
Laurène FenwarthLaboratory of Hematology, Lille University Hospital, Lille, France.ORCID http://orcid.org/0000-0003-2808-4843
Vincent MarmousetDepartment of Hematology, Institut Paoli Calmettes, Marseille, France.
Cécile PautasDepartment of Hematology, Henri-Mondor, Créteil, France.
Thomas CluzeauDepartment of Hematology, University Hospital of Cote d'Azur, CHU de Nice, Nice, France.ORCID http://orcid.org/0000-0002-6745-1127
Delphine LebonDepartment of Hematology, Amiens University Hospital, Amiens, France.ORCID http://orcid.org/0000-0002-4073-1559
Madalina UzunovDepartment of Hematology, Hôpital Pitié-Salpêtrière, Assistance publique Hôpitaux de Paris and Paris University, Paris, France.
Patricio PereyraDepartment of Hematology, Centre Antoine Lacassagne, Nice, France.
Maël HeibligLaboratory of Hematology, Lyon Sud University Hospital, Lyon, France.
Jean-Valère MalfusonDepartment of Hematology, Percy Hospital, Clamart, France.
Laure FarnaultHematology and Cellular Therapy Department, La Conception, University Hospital of Marseille, Marseille, France.
Pierre-Yves DumasDepartment of Hematology, Bordeaux University Hospital, Pessac, France.ORCID http://orcid.org/0000-0003-0119-3548
Julia HieulleDepartment of Hematology, Hôpital de Roubaix, Roubaix, France.ORCID http://orcid.org/0009-0005-0947-2789
Sarah BertoliCentre Hospitalo-universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Université de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0003-1084-2781
Sylvain ChantepieDepartment of Hematology, Caen University Hospital, Caen, France.
Nathalie AugerDepartment of Biologie et pathologie médicales, Gustave Roussy, Université Paris-Saclay, Villejuif, France.ORCID http://orcid.org/0000-0002-9744-4470
Audrey BidetLaboratory of Hematology, Bordeaux University Hospital, Pessac, France.ORCID http://orcid.org/0000-0003-0992-8377
Marie-Joelle MozziconacciLaboratory of Hematology, Institut Paoli Calmettes, Marseille, France.
Augustin BoudryLaboratory of Hematology, Lille University Hospital, Lille, France.ORCID http://orcid.org/0000-0002-9154-1085
Isabelle LuquetCentre Hospitalo-universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Université de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0001-7891-5727
Laureen ChatLaboratory of Hematology, Hôpital Saint Louis, Assistance publique Hôpitaux de Paris and Paris University, Paris, France.
Romain LoyauxDepartment of Biologie et pathologie médicales, Gustave Roussy, Université Paris-Saclay, Villejuif, France.ORCID http://orcid.org/0000-0001-5644-926X
Lina El-MurDepartment of Hematology, Gustave Roussy, Villejuif, France.
Emmanuelle ClappierLaboratory of Hematology, Hôpital Saint Louis, Assistance publique Hôpitaux de Paris and Paris University, Paris, France.
Claude GardinDepartment of Hematology, Avicenne Hospital, Avicenne, France.
Mathilde HunaultMaladies du Sang CHU Angers, CRCI2NA, SFR ICAT, et FHU GOAL, Angers, France.ORCID http://orcid.org/0000-0001-7777-5216
Stéphane De BottonDepartment of Hematology, Avicenne Hospital, Avicenne, France.ORCID http://orcid.org/0000-0002-8126-4942
Arnaud PigneuxDepartment of Hematology, Bordeaux University Hospital, Pessac, France.ORCID http://orcid.org/0000-0001-5479-0261
Dominique PentherDepartment of Oncology Genetic Centre Henri Becquerel, Rouen, France.
Eric DelabesseCentre Hospitalo-universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Université de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0002-0928-0753
Raphael ItzyksonDepartment of Hematology, Hôpital Saint Louis, Assistance publique Hôpitaux de Paris and Paris University, Paris, France.ORCID http://orcid.org/0000-0003-2139-6262
Claude PreudhommeLaboratory of Hematology, Lille University Hospital, Lille, France.
Hervé DombretDepartment of Hematology, Hôpital Saint Louis, Assistance publique Hôpitaux de Paris and Paris University, Paris, France.
Christian RecherCentre Hospitalo-universitaire de Toulouse, Institut Universitaire du Cancer de Toulouse-Oncopole, Université de Toulouse, Toulouse, France.ORCID http://orcid.org/0000-0002-3332-4525
Nicolas Duployez *Laboratory of Hematology, Lille University Hospital, Lille, France.ORCID http://orcid.org/0000-0002-3927-1022
Jean-Baptiste Micol *Department of Hematology, Avicenne Hospital, Avicenne, France. jeanbaptiste.micol@gustaveroussy.fr.ORCID http://orcid.org/0000-0003-0934-294X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a large cohort of 95 adult patients with acute myeloid leukemia (AML) harboring NUP98 rearrangements (NUP98r). Patient characteristics included a young age (median 50 years [IQR 38-64]), 20% of therapy-related AML, a high WBC count (median 52×10

Indexed as

Gene RearrangementLeukemia, Myeloid, AcuteMutationNuclear Pore Complex ProteinsAdultDNA Mutational AnalysisFemalefms-Like Tyrosine Kinase 3HumansMaleMiddle AgedOncogene Proteins, FusionPrognosisfms-Like Tyrosine Kinase 3nuclear pore complex protein 98Nuclear Pore Complex ProteinsNup98 protein, humanOncogene Proteins, Fusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.