ArticleNature communications2026
Identification and quantification of intracellular N-acetylglucosamine modified glycoRNAs.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
GlycoRNAs are recently discovered glycoconjugates, their different components and distributions are urgently-to-study issues. Here, we design a general paradigm to study glycoRNA from multiple perspectives. Using the metabolic labelling technology and the designed fluorescent DNA probes, the N-acetylglucosamine (GlcNAc) modified Y5 RNA is identified to be mainly in nucleus by fluorescence resonance energy transfer imaging. After it is collected by a target-specific capture procedure, the component of GlcNAc conjugated ribonucleotide can be determined by gel electrophoresis and mass spectrometric analysis. The levels of intracellular GlcNAc modified Y5 RNA in different cell lines are in situ quantified with a GlcNAc-specific in situ hybridization-mediated proximity ligation assay with single-cell and single-molecule resolution. These findings innovate the distribution and quantitation information of glycoRNAs, which greatly promotes the functional research of glycoRNAs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.