ArticleScientific reports2026
Identifying high-risk eyes for glaucoma surgery in cytomegalovirus anterior uveitis.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cytomegalovirus (CMV) has recently emerged as a significant cause of anterior uveitis (AU) with intraocular pressure (IOP) elevation and corneal endothelial damage. The purpose of this study is to investigate the long-term prognostic factors for glaucoma surgery in patients with CMV-AU. In this retrospective cohort study, immunocompetent patients with CMV-AU were included from one academic institution and a uveitis-specialized private clinic between May 2015 and Mar 2024. Upon confirmation of polymerase-chain-reaction results, patients received anti-viral therapy (oral valganciclovir or 2% topical ganciclovir). When intraocular pressure was not controlled, glaucoma surgery (glaucoma filtering surgery or glaucoma drainage device) were performed. Indicators of glaucoma surgery were analyzed using Kaplan-Meir survival analyses and Cox-proportional hazard model. A total of 149 consecutive patients with CMV-AU included with a mean age of 44.5 ± 16.5 years; 65.1% being male. The baseline corneal endothelial cell (EC) density in affected eyes was 2088 ± 695 cells/mm
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