ArticleScientific reports2026
Family burden of disease in pemphigus: a cross-sectional survey.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pemphigus is a rare, chronic, recurrent, and life-threatening autoimmune blistering skin disease that imposes a substantial burden on patients, their families, and society. However, information regarding the familial burden associated with pemphigus remains limited. This study aimed to assess the family burden experienced by caregivers of pemphigus patients and to identify relevant contributing factors. From December 2020 to December 2022, a total of 163 patient-caregiver dyads were enrolled in the study. Caregivers completed the Family Burden Scale of Diseases. Univariate logistic regression and multivariate logistic regression were utilized to explore factors influencing family burden. Among the 163 caregivers included in the study, the median Family Burden Scale score was 26 (IQR: 18-36), with 94 caregivers (57.7%) reporting moderate to severe family burden. In the multivariate logistic regression analysis, several factors were found to be significantly associated with family burden among pemphigus patients: medical insurance (adjusted odds ratio [aOR] 3.122, 95% confidence interval [CI] 1.749-5.574), disease type (aOR 0.201, 95% CI 0.050-0.803), Pemphigus Disease Area Index score (aOR 1.116, 95% CI 1.054-1.181), degree of disease severity (aOR 2.089, 95% CI 1.029-4.238), presence of comorbidities (aOR 3.712, 95% CI 1.378-9.999), and caregiver gender (aOR 3.244, 95% CI 1.258-8.362). This study confirms that pemphigus imposes a significant burden on families, highlighting the necessity for healthcare providers to develop and implement family-centered support programs aimed at alleviating this burden.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.