Evidence map›Paper›PMID 42119361›Full record

Trial reportGeneral hospital psychiatry

Bipolar disorder measurement-based care: Two-phase trial in primary care.

Joseph M Cerimele, Brittany E Blanchard, William Leasure, Jin Hong Park, Erin Chase, John C Fortney

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph M CerimeleUniversity of Cincinnati College of Medicine, Department of Psychiatry and Behavioral Neuroscience, Cincinnati, OH, USA. Electronic address: joseph.cerimele@uc.edu.
Brittany E BlanchardUniversity of Washington School of Medicine, Department of Psychiatry & Behavioral Sciences, Seattle, Washington, USA.
William LeasureMayo Clinic, Department of Psychiatry & Psychology, Division of Integrated Behavioral Health, Rochester, MN, USA.
Jin Hong ParkMayo Clinic, Department of Psychiatry & Psychology, Division of Integrated Behavioral Health, Rochester, MN, USA.
Erin ChaseUniversity of Washington School of Medicine, Department of Psychiatry & Behavioral Sciences, Seattle, Washington, USA.
John C FortneyUniversity of Washington School of Medicine, Department of Psychiatry & Behavioral Sciences, Seattle, Washington, USA; Department of Veterans Affairs, HSR&D Center of Innovation for Veteran-Centered and Value-Driven Care, VA Puget Sound Health Care System, Seattle, WA, USA.

Funding

NCCIH Supplement to NCATS/CTSA Program for KL2 Scholars - M. SoddersKL2TR002317 · NCATS · UNIVERSITY OF WASHINGTON · PI Christy Michelle McKinney · 2017 to 2026
$14.5M
Bipolar disorder measures in clinical careR34MH125935 · NIMH · UNIVERSITY OF WASHINGTON · PI BLANCHARD, BRITTANY ELIZABETH, CERIMELE, JOSEPH M. · 2022 to 2024
$720k
NCATS NIH HHS KL2 TR002317NIMH NIH HHS R34 MH125935
6 · The paper itself

Abstract

objectiveTo assess feasibility and preliminary effectiveness of measurement-based care (MBC) for bipolar disorder.

methodsWe recruited adults with bipolar disorder in community primary care clinics with integrated mental health services. We used the Patient Mania Questionnaire-9 (PMQ-9, manic symptoms) and Patient Health Questionnaire-9 (PHQ-9, depressive symptoms) for MBC. In the lead-in phase, a fidelity score assessed adherence to MBC. In the randomization phase, patients were randomized to 6 months of MBC or usual care. The primary outcome was number of treatment changes. Baseline and 6-month participant surveys assessed other outcomes. We used a Mann-Whitney U test and descriptive statistics.

resultsIn the lead-in phase, five psychiatrists and fifteen patients participated, with symptom measures completed at all participant visits (n = 40 visits). In the randomization phase, all invited psychiatrists (n = 6) and psychiatric advanced practice registered nurses (n = 3) participated. Thirty patients were consented and randomized. There was no statistically significant difference in the number of treatment changes between groups (Med

conclusionGiven the feasibility and preliminary effectiveness of MBC for bipolar disorder in primary care, a larger fully powered trial should test if MBC yields greater reduction in symptoms and increased quality of life.

Indexed as

Bipolar DisorderOutcome Assessment, Health CarePrimary Health CareAdultFeasibility StudiesFemaleHumansMaleMiddle AgedPsychiatristsBipolar disorderFeasibility trialMeasurement-based carePrimary careTreat-to-target

Identifiers

PMID42119361
PMCPMC13285966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.