Evidence map›Paper›PMID 42119066›Full record

ArticleThe Plant journal : for cell and molecular biology2026

TCP21 negatively regulates photomorphogenesis by integrating phyB- and HY5-mediated signaling pathways in Arabidopsis.

Mengdi Zhang, Yueqin Heng, Siqi Yan, Mengsi Sun, Jian Li, Hua Zhou, Xing Wang Deng

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Article in The Plant journal : for cell and molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengdi ZhangShenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Department of Biology, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen, 518055, China.
Yueqin HengState Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Laboratory for Lingnan Modern Agriculture, College of Life Sciences, South China Agricultural University, Guangzhou, 510642, China.
Siqi YanShenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Department of Biology, School of Life Sciences, Institute of Plant and Food Science, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID https://orcid.org/0009-0009-4562-3256
Mengsi SunCollege of Horticulture and Landscape, Hunan Agricultural University, Changsha, 410000, China.
Jian LiCollege of Life Sciences, Nanjing Normal University, Nanjing, 210046, China.ORCID https://orcid.org/0000-0002-1287-8932
Hua ZhouLaboratory of Plant and Environment Interaction Study, Tsientang Institute for Advanced Study, Hangzhou, 310024, China.ORCID https://orcid.org/0000-0002-4944-058X
Xing Wang DengLaboratory of Plant and Environment Interaction Study, Tsientang Institute for Advanced Study, Hangzhou, 310024, China.

Funding

Hangzhou Tsientang Education FoundationNational Natural Science Foundation of China (NSFC) Key Program 32230006Natural Science Foundation of Guangdong Province 2023A1515012564Shenzhen Science and Technology Program ZDSYS20230626091659010Southern University of Science and Technology Y01226026
6 · The paper itself

Abstract

The phytochrome B (phyB)-transcription factor signaling module plays a critical role in regulating photomorphogenesis. In this study, TCP21, a member of the Class I TCP transcription factor family, was identified as a direct interacting partner of phyB. TCP21 negatively regulates photomorphogenesis through downregulating HY5 expression and repressing the transcriptional activity of HY5. Moreover, phyB physically interacts with TCP21 and inhibits its transcriptional activity. Notably, phyB outcompetes HY5 for binding to TCP21, thereby attenuating the interaction between TCP21 and HY5 and alleviating TCP21-mediated repression of HY5 DNA-binding ability. Collectively, these findings establish TCP21 as a key component within the phyB-HY5 signaling module, contributing to plant adaptation to dynamic light environments.

Indexed as

ArabidopsisArabidopsis ProteinsBasic-Leucine Zipper Transcription FactorsNuclear ProteinsPhytochrome BTranscription FactorsGene Expression Regulation, PlantLightSignal TransductionArabidopsis ProteinsBasic-Leucine Zipper Transcription FactorsHY5 protein, ArabidopsisNuclear ProteinsPHYB protein, ArabidopsisPhytochrome BTranscription FactorsArabidopsisHY5photomorphogenesisphyBTCP21

Identifiers

PMID42119066
PMCPMC13167141

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.