Evidence map›Paper›PMID 42118661›Full record

ArticleSTAR protocols2026

Protocol for preparing pH-sensitive Mg-DOX liposomes by remote loading for treatment of acidic tumors.

Yu Yang, Baiyang Lu, Xin Tang, Miaomiao Zhang, Zhiqiang Hong, Shihong Li

Abstract read
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In one paragraph

Article in STAR protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu YangDepartment of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Baiyang LuState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Xin TangDepartment of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China; Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China.
Miaomiao ZhangDepartment of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Zhiqiang HongState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical College of Soochow University, Suzhou 215123, China.
Shihong LiDepartment of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Suzhou Medical College of Soochow University, Suzhou 215123, China; Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, China. Electronic address: lishihong@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficient delivery and pH-sensitive release of anti-tumor drugs by nanocarriers have been recognized as an appealing strategy to enhance the chemotherapeutic efficacy toward acidic tumors. Here, we present a protocol for preparing magnesium-doxorubicin (Mg-DOX) liposomes as a pH-sensitive drug delivery system with a remote-loading approach. We detail the steps for the construction of MgAc

Indexed as

DoxorubicinMagnesiumNanoparticle Drug Delivery SystemAntibiotics, AntineoplasticDrug CompoundingHumansHydrogen-Ion ConcentrationLiposomesNeoplasmsAntibiotics, AntineoplasticDoxorubicinLiposomesMagnesiumNanoparticle Drug Delivery SystemBiotechnology and bioengineeringCancerChemistryMaterial sciences

Identifiers

PMID42118661
PMCPMC13195598

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.