Evidence map›Paper›PMID 42118377›Full record

ArticleEuropean journal of pediatrics2026

Long-term ambient temperature and asthma severity and hospitalization in children: a population-based study.

Firdian Makrufardi, Hsiao-Chi Chuang, Yuan-Chien Lin, Kin-Fai Ho, Kian Fan Chung, Marc Chadeau-Hyam, Desy Rusmawatiningtyas, Eggi Arguni, Indah Kartika Murni, Sheng-Chieh Lin

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Article in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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10 authors.

Firdian Makrufardi *International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hsiao-Chi Chuang *School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Yuan-Chien LinDepartment of Civil Engineering, National Central University, Taoyuan City, Taiwan.
Kin-Fai HoJC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China.
Kian Fan ChungNational Heart and Lung Institute, Imperial College London, London, UK.
Marc Chadeau-HyamDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Desy RusmawatiningtyasDepartment of Child Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Eggi ArguniDepartment of Child Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Indah Kartika MurniDepartment of Child Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada-Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Sheng-Chieh LinDepartment of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. jacklinbox@tmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To estimate the risk projection of temperature on pediatric asthma severity and hospitalization under four Shared Socioeconomic Pathways (SSPs) possible future climate scenarios using the Intergovernmental Panel on Climate Change (IPCC) model. A retrospective study was conducted involving 102,160 pediatric asthma patients from the Taipei Medical University Clinical Research Database (TMUCRD). We utilized global climate model (GCM) outputs to project future temperature for each subject from optimistic (SSP126) to pessimistic (SSP585) projections. A multinomial logistic regression was used to examine the odds ratio of pediatric asthma severity and hospitalization. A 1 °C increase in 1-year, 5-year, and 10-year average temperatures was associated with 1.004-fold (95% CI: 1.003-1.005) and 1.332-fold (95% CI: 1.327-1.338), 1.004-fold (95% CI: 1.002-1.005) and 1.303-fold (95% CI: 1.298-1.308), and 1.005-fold (95% CI: 1.004-1.006) and 1.282-fold (95% CI: 1.278-1.287) increase in the OR for mild persistent and hospitalization of pediatric asthma. We observed a non-linear association between temperature under SSP126, SSP245, SSP370 and SSP585 with moderate persistent pediatric asthma and pediatric asthma hospitalization, with the highest OR increases observed in 2033 at 33.4% and 32.3%, 27.6% and 32.3%, 29.1% and 32.4%, and 27.2% and 32.3%, respectively. Conclusion: Projected future temperature changes as a result of climate change may be associated with a possible increase in pediatric asthma severity and hospitalization in the coming years, with an expected increase of 8.0% and 2.5% per 1 °C increase, respectively. Pediatric asthma patients may be more susceptible to poorer outcomes under climate change in the future. What is Known: • Rising temperatures have been linked to increased asthma severity and hospitalization. • Climate change worsening pediatric asthma outcomes and increasing the healthcare burden. What is New: • Long-term exposure to rising ambient temperatures and PM

Indexed as

AsthmaClimate ChangeHospitalizationTemperatureAdolescentChildChild, PreschoolFemaleHumansInfantLogistic ModelsMaleRetrospective StudiesSeverity of Illness IndexTaiwanAsthmaClimate changeExtreme weatherPediatricThermal

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.