Observational studyArchives of orthopaedic and trauma surgery2026
Impact of frailty on 12-month patient-reported outcomes after posterior lumbar fusion surgery.
Observational study in Archives of orthopaedic and trauma surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
introductionFrailty might increase the risk for postoperative complications and death. It is not well understood how frailty influences patient-reported outcomes (PROs) in spine surgery. The objective is to investigate on the impact of frailty on PROs 1-year after lumbar fusion. MATERIALS AND
methodsThis was a prospective observational study of patients undergoing open posterior lumbar fusion for degenerative conditions with 12-month follow-up (12 M-FU). The modified 5-item frailty index (mFI-5) score was determined preoperatively. PROs included the Oswestry-Disability-Index (ODI), 12-item Short-Form-Healthy-Survey with Physical (PCS-12) and Mental-Component-Score (MCS-12) and Numerical-Rating-Scale (back/leg pain) before surgery and 6 weeks, 3, 6 and 12 months (6 W, 3 M, 6 M, 12 M) postoperatively. PROs were compared between groups stratified as frail (mFI-5 ≥ 2), pre-frail (mFI-5 = 1) and non-frail (mFI-5 = 0). PRO changes at 12 M-FU were evaluated with substantial clinical benefit (SCB) metrics. Regression models were used to determine associations between mFI-5 and PROs.
results135 patients (52.6% female, 62.1 years, BMI 29.1 kg/m
conclusionsFrailty patients reached a smaller ODI improvement at 12 M-FU. Frailty might be associated with worse PROs one year after elective lumbar fusion, nevertheless, even frail patients are likely to benefit from an improved quality of life after surgery. The mFI-5 can be assessed preoperatively for risk stratification and used to counsel patients on their expectations for health-related quality of life.
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