ReviewInfectious diseases and therapy2026
When Culture Results Don't Tell the Whole Story: A Practical Review of Antibiotics Pitfalls for Clinical Decision-Making.
Review in Infectious diseases and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial susceptibility testing has long served as the cornerstone of infectious disease management, guiding clinicians toward selecting appropriate therapeutic agents. However, an emerging body of evidence demonstrates that blind adherence to culture and sensitivity reports can lead to therapeutic failures, increased mortality, and propagation of antimicrobial resistance. This review critically examines clinical scenarios where conventional antimicrobial susceptibility testing results may be discordant with clinical outcomes, emphasizing the critical importance of integrating microbiological data with pharmacokinetic principles, host factors, and evidence-based guidelines. By understanding the limitations of culture-based testing including intrinsic resistance mechanisms, inducible resistance patterns, site-specific pharmacodynamic considerations, and the distinction between colonization and infection, clinicians can make more informed therapeutic decisions that optimize patient outcomes while preserving the antimicrobial arsenal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.