Evidence map›Paper›PMID 42117999›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society

International Survey on Screening and Management of Strongyloidiasis in Solid Organ Transplant Patients.

Jacques Simkins, Akshatha Ravindra, Cameron R Wolfe, Alessandra Mularoni, Monica Slavin, Ines Ushiro-Lumb, John W Baddley, Jonathan Hand, Stephanie Pouch, Maricar Malinis and 6 more

Abstract read
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jacques SimkinsDivision of Infectious Diseases. University of Miami School of Medicine, Miami, Florida, USA.ORCID https://orcid.org/0000-0001-9626-0760
Akshatha RavindraConsultant Infectious Diseases & Infection Control Officer, Kauvery Hospitals, Bangalore, India.ORCID https://orcid.org/0000-0002-1850-9329
Cameron R WolfeDivision of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-5365-5030
Alessandra MularoniIstituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione, Palermo, Italy.ORCID https://orcid.org/0000-0001-8612-5581
Monica SlavinDepartment of Infectious Diseases, Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.ORCID https://orcid.org/0000-0002-8443-314X
Ines Ushiro-LumbNational Health Service Blood and Transplant, London, UK.ORCID https://orcid.org/0000-0003-0989-8091
John W BaddleyDivision of Infectious Diseases, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Jonathan HandDepartment of Infectious Diseases, Ochsner Health, University of Queensland School of Medicine, Ochsner Clinical School, New Orleans, Louisiana, USA.ORCID https://orcid.org/0000-0002-5752-9576
Stephanie PouchDivision of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-5628-2444
Maricar MalinisSection of Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID https://orcid.org/0000-0002-5720-9994
Maristela P FreireHospital Das Clinicas, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil.ORCID https://orcid.org/0000-0002-9691-192X
Marcelo RadisicInstituto De Trasplante De Alta Complejidad, Buenos Aires, Argentina.
Matthew B RobertsInfectious Diseases Unit, Royal Adelaide Hospital, Adelaide, Australia.ORCID https://orcid.org/0000-0003-0869-6463
Ban Hock TanSinghealth Duke Transplant Centre, Singapore, Singapore.
Siriorn WatcharanananDivision of Infectious Disease, Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-8464-9709
Wanessa T ClementeTransplant Program, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0003-0848-3740

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStrongyloides stercoralis infection can be associated with high mortality in solid organ transplant (SOT) recipients, yet global practices regarding screening and management remain poorly characterized. We conducted an international survey to evaluate knowledge, screening, and management practices among healthcare workers (HCWs) involved in SOT care.

methodsWe performed a cross-sectional, web-based survey of HCWs caring for SOT candidates and recipients. The survey assessed provider characteristics, knowledge of strongyloidiasis, as well as screening and management practices. Descriptive statistics were used to summarize responses.

resultsA total of 101 HCWs responded, including 65 (64%) infectious diseases (ID) providers and 36 (36%) non-ID providers. Knowledge gaps were identified regarding transmission and mortality, particularly among non-ID providers. Overall, 85% of respondents reported screening SOT candidates for S. stercoralis; among those who screen, serology is the most commonly used method. Screening strategies varied by geographic region, with universal screening more common in endemic areas and targeted screening in non-endemic regions. Management practices, including approaches to indeterminate or negative test results, showed substantial heterogeneity.

conclusionsThis international survey demonstrates considerable variability in knowledge, screening, and management of strongyloidiasis among HCWs involved in SOT care. These findings highlight opportunities for improved education, clearer guidance, and greater standardization of practices related to Strongyloides infection to avoid unnecessary morbidity.

Indexed as

Health PersonnelMass ScreeningOrgan TransplantationStrongyloidiasisAdultAnimalsCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedStrongyloides stercoralisSurveys and QuestionnairesTransplant Recipientshealthcare workersmanagementscreeningsolid organ transplantstrongyloidiasissurvey

Identifiers

PMID42117999
PMCPMC13450342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.