Evidence map›Paper›PMID 42117636›Full record

ArticleApplied and environmental microbiology2026

Reciprocal cross-feeding between bacteria can limit the emergence of metabolic dependencies.

Ying-Chih Chuang, Megan G Behringer, Gillian E Patton, Jordan T Bird, Jeffrey L Mazny, Jennifer R Gliessman, Crystal E Love, Ankur B Dalia, James B McKinlay

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ying-Chih ChuangDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0002-3626-6631
Megan G BehringerDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0000-0001-7036-6014
Gillian E PattonDepartment of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0009-0001-7367-4132
Jordan T BirdBattelle Memorial Institute, Columbus, Ohio, USA.
Jeffrey L MaznyDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Jennifer R GliessmanDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Crystal E LoveDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0001-9988-7067
Ankur B DaliaDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0003-2203-1230
James B McKinlayDepartment of Biology, Indiana University, Bloomington, Indiana, USA.ORCID 0000-0003-2401-6229

Funding

Mechanisms and regulation of horizontal gene transfer by natural transformation in Vibrio choleraeR35GM128674 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI Ankur Dalia · 2018 to 2026
$3.8M
Using Experimental Evolution to Evaluate Environmental Effects on Microbial Mutation and AdaptationR35GM150625 · NIGMS · VANDERBILT UNIVERSITY · PI Megan Grace Behringer · 2023 to 2026
$1.8M
Army Research Office W911NF-14-1-0411Army Research Office W911NF-17-1-0159National Science Foundation MCB-1749489NIGMS NIH HHS R35 GM128674NIGMS NIH HHS R35 GM150625NIH HHS R35GM128674NIH HHS R35GM150625
6 · The paper itself

Abstract

Cross-feeding is prevalent in microbial communities. Through time, cross-feeding is thought to enrich for loss-of-function mutations, thereby creating or reinforcing dependencies between community members. However, few studies have compared how cross-feeding affects the evolutionary trajectory of partners compared to monoculture conditions. Here, we compared mutations that were differentially enriched in bacterial monocultures versus cocultures pairing phototrophic

Indexed as

Escherichia coliMicrobial InteractionsRhodopseudomonasAdenineCarbonCoculture TechniquesFermentationIronMutationNitrogenAdenineCarbonIronNitrogenadaptive gene lossfermentationhydrogenmetabolismmicrobial ecologymicrobial physiologyphototrophypurinesRhodopseudomonassiderophores

Identifiers

PMID42117636
PMCPMC13274399

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.