Evidence map›Paper›PMID 42117554›Full record

ArticleBioMed research international2026

Antibacterial Activity of Corryocactus brevistylus (Sanky) Methanolic Extract Against Staphylococcus aureus and Enterococcus faecalis.

Ronald Aquino-Ortega, Hugo Carrillo-Ng, Luz María Paucar-Menacho, Miguel Angel Aguilar-Luis, Wilmer Silva-Caso, Yulissa Milagros Salvatierra-Pajuelo, Ritva Repo-Carrasco-Valencia, Juana Del Valle-Mendoza

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In one paragraph

Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ronald Aquino-OrtegaBiomedicine Laboratory, Research Center of the Faculty of Health Sciences, Peruvian University of Applied Sciences, Lima, Peru, upc.edu.pe.
Hugo Carrillo-NgBiomedicine Laboratory, Research Center of the Faculty of Health Sciences, Peruvian University of Applied Sciences, Lima, Peru, upc.edu.pe.
Luz María Paucar-MenachoAcademic Department of Agroindustry and Agronomy, Faculty of Engineering, National University of Santa, Chimbote, Peru.
Miguel Angel Aguilar-LuisBiomedicine Laboratory, Research Center of the Faculty of Health Sciences, Peruvian University of Applied Sciences, Lima, Peru, upc.edu.pe.
Wilmer Silva-CasoBiomedicine Laboratory, Research Center of the Faculty of Health Sciences, Peruvian University of Applied Sciences, Lima, Peru, upc.edu.pe.ORCID https://orcid.org/0000-0003-1086-8084
Yulissa Milagros Salvatierra-PajueloAcademic Department of Agroindustry and Agronomy, Faculty of Engineering, National University of Santa, Chimbote, Peru.
Ritva Repo-Carrasco-ValenciaFaculty of Food Industries, National Agrarian University La Molina, Lima, Peru.ORCID https://orcid.org/0000-0002-3656-2377
Juana Del Valle-MendozaBiomedicine Laboratory, Research Center of the Faculty of Health Sciences, Peruvian University of Applied Sciences, Lima, Peru, upc.edu.pe.ORCID https://orcid.org/0000-0002-6011-5040

Funding

Concytec-World Bank 02-2018-FONDECYT-BMDirección de Investigación-Universidad Peruana de Ciencias Aplicadas UPC-A-070-2020
6 · The paper itself

Abstract

backgroundStaphylococcus aureus and Enterococcus faecalis are bacteria for which new antibiotics are urgently needed. Corryocactus brevistylus is a Peruvian cactus with an antibacterial effect that has not yet been studied.

objectiveTo determine the antibacterial effect of C. brevistylus methanol extract against S. aureus (ATCC 6538) and E. faecalis (ATCC 29212).

methodsSanky fruits were extracted with methanol (1:2, w/v). Agar well diffusion tests were used by preparing wells with the experimental solutions cultivated in aerobic conditions for 24 h at 37°C. Six independent tests were prepared for each type of bacteria, using penicillin-streptomycin and chlorhexidine as positive controls. The MIC was determined using the microdilution method as described by the CLSI.

resultsThe antibacterial effect of the methanol extract was dose-dependent, with inhibition zones of 23.33 ± 0.72 and 24.34 ± 0.55 mm against S. aureus and E. faecalis, respectively, at the highest concentration. Meanwhile, penicillin-streptomycin (10 U) and chlorhexidine produced inhibition zones comparable to the extract at the highest concentration. The MIC achieved by the extract was 15.6 mg/mL for both S. aureus and E. faecalis, while the MBC for S. aureus was 62.5 mg/mL and for E. faecalis 31.3 mg/mL.

conclusionsWeak antibacterial potency was observed in the methanolic extract of C. brevistylus against the strains of S. aureus and E. faecalis.

Indexed as

Anti-Bacterial AgentsEnterococcus faecalisMethanolPlant ExtractsStaphylococcus aureusMicrobial Sensitivity TestsAnti-Bacterial AgentsMethanolPlant Extractsantimicrobial effectsCorryocactus brevistylusEnterococcus faecalissanky extractStaphylococcus aureus

Identifiers

PMID42117554
PMCPMC13162344

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.