Evidence map›Paper›PMID 42117532›Full record

ArticleThe journal of physical chemistry letters2026

Gel-Based NMR Method for Observing Submicrosecond Protein Dynamics at Atomic Resolution.

Xinyao Xiang, Mamata Basnet, Mouzhe Xie, Lei Bruschweiler-Li, R Brüschweiler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physical chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinyao XiangDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0002-8584-3642
Mamata BasnetDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Mouzhe XieSchool of Molecular Sciences, Arizona State University, , 551 E University Dr., Tempe, Arizona 85281, United States.
Lei Bruschweiler-LiDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
R BrüschweilerDepartment of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.ORCID 0000-0003-3649-4543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NMR spectroscopy is uniquely suitable of observing functionally important protein motions at atomic resolution under near-physiological conditions in solution. Longitudinal and transverse spin relaxation experiments report about fast subnanosecond and low nanosecond motions, but they are insensitive to slower motions. The recently introduced nanoparticle assisted spin relaxation (NASR) method increases the observation window into the submicrosecond range by measuring the increase in transverse relaxation by the presence of silica nanoparticles. It is demonstrated here how a similar effect can be observed via the transverse relaxation enhancement Δ

Indexed as

Nuclear Magnetic Resonance, BiomolecularProteinsAcrylic ResinsGelsNanoparticlesSilicon DioxideAcrylic ResinsGelsProteinsSilicon Dioxide

Identifiers

PMID42117532
PMCPMC13200236

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.