Evidence map›Paper›PMID 42117273›Full record

ArticleVeterinary pathology2026

Naturally occurring lysosomal storage disease consistent with neuronal ceroid lipofuscinosis in a group of 5 related captive rhesus macaques (

Katherine Olstad, Gabrielle Pastenkos, Javier Barrera-Zarate, Sreetharan Kanthaswamy, Rebecca Sammak, Marie-Josee Lemoy

Abstract read
In one paragraph

Article in Veterinary pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine OlstadUniversity of California, Davis, Davis, CA.ORCID 0000-0003-3894-0981
Gabrielle PastenkosUniversity of California, Davis, Davis, CA.
Javier Barrera-ZarateUniversity of California, Davis, Davis, CA.
Sreetharan KanthaswamyUniversity of California, Davis, Davis, CA.
Rebecca SammakUniversity of California, Davis, Davis, CA.
Marie-Josee LemoyUniversity of California, Davis, Davis, CA.

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
NIH HHS P51 OD011107
6 · The paper itself

Abstract

Lysosomal storage diseases (LSDs) are a diverse group of inherited disorders characterized by the accumulation of undegraded macromolecules within lysosomes, leading to cellular dysfunction and progressive organ damage. Neuronal ceroid lipofuscinosis (NCL) is a subset of LSDs defined by the accumulation of autofluorescent lipopigments in neurons and, in some cases, peripheral tissues. While naturally occurring LSDs have been documented in domestic and laboratory species, reports in nonhuman primates (NHPs) remain rare. This study describes an LSD in 5 related rhesus macaques (

Indexed as

Lysosomal Storage DiseasesMacaca mulattaMonkey DiseasesNeuronal Ceroid-LipofuscinosesAnimalsBrainCerebellumFemaleMaleMicroscopy, Electron, Transmissionautosomal recessive inheritancelysosomal storage diseaseneurodegenerationneurologicneuronal ceroid lipofuscinosisnonhuman primaterhesus macaque

Identifiers

PMID42117273
PMCPMC13317747

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.