SynthesisInternational journal of chronic obstructive pulmonary disease2026
Exercise Training Improves Depression and Anxiety in Patients with COPD: A Dose-Response Meta-Analysis of Randomized Controlled Trials.
Synthesis in International journal of chronic obstructive pulmonary disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Objective: To evaluate the effects of exercise training on depressive and anxiety symptoms in patients with chronic obstructive pulmonary disease (COPD). Methods: We searched PubMed, Embase, Cochrane Library, and Web of Science from inception to May 7, 2025, for randomized controlled trials (RCTs) investigating exercise training for depression or anxiety in COPD patients. Two researchers independently screened literature, extracted data, and assessed methodological quality. To reduce measurement heterogeneity, only studies reporting the Hospital Anxiety and Depression Scale (HADS-D for depression, HADS-A for anxiety) were included as outcome indicators. Meta-analysis was performed using a random-effects model, and subgroup analysis explored the influence of cumulative intervention duration. Results: Eleven RCTs involving 1208 COPD patients were included. Using HADS-D and HADS-A as outcome measures, exercise training significantly improved depressive symptoms [SMD = -0.35 (95% CI: -0.58, -0.12), Conclusion: Exercise training is an effective non-pharmacological intervention for depression and anxiety in COPD patients. Integrating exercise into comprehensive COPD management is recommended, with exploratory evidence suggesting benefit when cumulative durations exceed 1500 minutes. More high-quality, long-term follow-up RCTs are needed to clarify optimal exercise regimens and mechanisms.
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