Evidence map›Paper›PMID 42116982›Full record

ArticleCureus2026

The Effect of Case-Based Instruction on Physician Assistant Pharmacology Education.

Laney Henley, Seth M Alexander, Nicole Mihailovich, Jeanette Elfering, James J Fiordalisi

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Laney HenleyPharmacology, University of North Carolina School of Medicine, Chapel Hill, USA.
Seth M AlexanderHealth Sciences, University of North Carolina School of Medicine, Chapel Hill, USA.
Nicole MihailovichHealth Sciences, University of North Carolina School of Medicine, Chapel Hill, USA.
Jeanette ElferingHealth Sciences, University of North Carolina School of Medicine, Chapel Hill, USA.
James J FiordalisiPharmacology, University of North Carolina School of Medicine, Chapel Hill, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCase-based learning (CBL) is a widely adopted instructional method in medical education, guiding students through real-world scenarios to accomplish specific learning objectives. Despite literature supporting its use in medical education at the Undergraduate Medical Education (UME) level and in some other health professions, there is a lack of research surrounding its utility in physician assistant (PA) education compared to the more traditional, lecture-based instruction. This difference is particularly true in pharmacology, a subject well-suited for the application of basic science to clinical medicine through CBL.  Methods: Fifteen first-year PA students enrolled in an entry-level pharmacology course participated in six pharmacology learning cycles, each learning cycle consisting of a discrete didactic session followed by a corresponding case-based learning session on the same topic. All first-year students enrolled in the program were allowed to participate voluntarily in the data collection; however, the curriculum was required for all students. For each topic, students completed multiple-choice evaluations at three time points: before didactic teaching sessions, after didactic teaching sessions but before case-based sessions, and after case-based sessions. At the conclusion of the six learning cycles, students completed a 12-item Likert survey to assess their perspectives on the CBL sessions.  Results: The average student score across all six case evaluations demonstrated a statistically significant increase in average scores from predidactic (mean = 31% correct; SD = 8.0) to the postdidactic evaluations (p = 0.01; mean = 42%; SD = 13), and then again to postdidactic to post-CBL evaluations (p < 0.01; mean = 53%; SD = 15). Evaluations within individual learning cycles, however, showed varying results across assessments. Students felt CBL improved their understanding and prepared them for their board exams (73.33% agree or strongly agree, N = 11). However, students had slightly mixed opinions about how useful CBL was for their understanding of the learning topics compared with their didactics, and positive opinions on CBL being introduced as a new learning method and its impact on board exam preparation.

conclusionsCBL is an effective learning method in supplementing traditional didactic teaching in PA pharmacology education, leading to significant learning gains and favorable student feedback. Unlike prior studies that compared CBL directly with conventional teaching methods, this study demonstrates the supplementary benefit of CBL.

Indexed as

case-based learningcomparative teachinglearning retentionpharmacologyphysician assistant education

Identifiers

PMID42116982
PMCPMC13157861

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.