Evidence map›Paper›PMID 42116902›Full record

ReviewSurgical neurology international2026

Gross-total resection of Koos grade IV sporadic pediatric-spectrum vestibular schwannoma: A case report and review of the literature.

Rebecca Garner, Jeff F Zhang, Aydin Kaghazchi, Marissa Koscielski, John Na, Ady Kendler, Daniel Sun, Jonathan A Forbes

Abstract readReview
In one paragraph

Review in Surgical neurology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rebecca GarnerDepartment of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
Jeff F ZhangDepartment of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
Aydin KaghazchiDepartment of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
Marissa KoscielskiDepartment of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
John NaDepartment of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
Ady KendlerDepartment of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
Daniel SunDepartment of Otolaryngology, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.
Jonathan A ForbesDepartment of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sporadic, unilateral pediatric-spectrum vestibular schwannomas (PSVSs), which occur in patients 21 years or younger without a diagnosis of neurofibromatosis type 2, are rare tumors with an estimated incidence of less than 0.1/100,000 children. A subset of PSVS tumors (designated Koos grade IV PSVSs) exhibits significant brainstem compression and poses unique management challenges. Methods: A systematic review of the PubMed database was conducted for all case reports, case series, meta-analyses, and clinical trials involving patients with PSVS, along with one patient from our institution. Data related to patient demographics, tumor size, Koos grading, surgical approach, number of surgical resections, preoperative and postoperative House-Brackmann (HB) grade, and postoperative complications and treatment were recorded. Results: We review the case of a 21-year-old female who presented with headaches, slight facial droop, and diplopia and was found to have a 3.7 cm Koos grade IV PSVS. Our technique of using an extended retrosigmoid craniotomy along with a navigated Sonopet ultrasonic aspirator facilitated a gross total resection with resolution of preoperative symptoms. Our literature review showed that 53.8% of Koos grade IV patients had a postoperative HB grade of III or higher, and a gross-total resection was only achieved in 57.1% of patients. Conclusion: This study illustrates the surgical complexity of Koos IV PSVS resection and underscores the need to further develop innovative surgical techniques (such as the use of a navigated ultrasonic aspirator and an extended retrosigmoid craniotomy as presented in this report) to improve surgical visualization and operative efficiency while decreasing neurologic morbidity.

Indexed as

Koos grade IVPediatric neurosurgeryUltrasonic aspiratorVestibular schwannoma

Identifiers

PMID42116902
PMCPMC13157902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.