Evidence map›Paper›PMID 42116714›Full record

ArticleCell biochemistry and function2026

Shear Stress as a Driver of Retinal Müller Glia Survival and Fibrotic Reprogramming.

Laura Prieto-López, Christian van Oterendorp, Elena Vecino, Xandra Pereiro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell biochemistry and function, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura Prieto-LópezDepartment of Cell Biology and Histology, Experimental Ophthalmo-Biology Group, University of Basque Country UPV/EHU, Leioa, Spain.
Christian van OterendorpDepartment of Ophthalmology, University Medical Center, Göttingen, Germany.
Elena VecinoDepartment of Cell Biology and Histology, Experimental Ophthalmo-Biology Group, University of Basque Country UPV/EHU, Leioa, Spain.
Xandra PereiroDepartment of Cell Biology and Histology, Experimental Ophthalmo-Biology Group, University of Basque Country UPV/EHU, Leioa, Spain.

Funding

Friends of the Göttingen Eye Hospital AssociationFundación Jesús de Gangoiti BarreraGrupos Consolidados Gobierno Vasco IT1510-22MINECO-Generación de Conocimiento MICIU/AEI/10.13039/501100011033 (PID2023-152778OB-I00)
6 · The paper itself

Abstract

The retina is highly influenced by mechanical cues such as intraocular fluid movement and blood flow, generating shear stress implicated in both retinal development and pathology. Müller glia, as retinal mechanosensors, are uniquely positioned to respond to such forces. This study examined Müller glia responses to flow-induced shear stress. Primary adult rat Müller glia were cultured in a single-channel microfluidic system and exposed to fluid shear stress (10

Indexed as

Ependymoglial CellsRetinaStress, MechanicalAnimalsCells, CulturedCell SurvivalExtracellular MatrixFibrosisFocal Adhesion Protein-Tyrosine KinasesNeurogliaRatsRats, Sprague-DawleyTransforming Growth Factor beta1TRPV Cation ChannelsFocal Adhesion Protein-Tyrosine KinasesTransforming Growth Factor beta1Trpv4 protein, ratTRPV Cation Channelsextracellular matrixflowMüller gliashear stressTGF‐β1TRPV4

Identifiers

PMID42116714
PMCPMC13161832

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.