Evidence map›Paper›PMID 42116410›Full record

ArticleMedicine2026

Efficacy and safety of modified transurethral thulium laser enucleation-resection with apical vaporization cutting versus anatomic thulium laser enucleation for large-volume (> 80 ml) benign prostatic hyperplasia: A retrospective comparative study.

Wenbin Li, Jianhua Zhang, Jie Guo, Lan Wang, Yujie Ma, Junqing Hou, Song Li

Abstract readComparative Study
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenbin LiDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.
Jianhua ZhangDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.
Jie GuoDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.
Lan WangDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.
Yujie MaDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.
Junqing HouDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.
Song LiDepartment of Urology, Kaifeng155 Hospital, China RongTong Medical Healthcare Group Co.Ltd., Kaifeng, China.ORCID 0009-0002-0113-3115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the perioperative outcomes, efficacy, and safety of modified transurethral thulium laser enucleation-resection (ThuLERP) versus standard anatomic thulium laser enucleation (ThuLEP) for large-volume benign prostatic hyperplasia (BPH) (> 80 ml), with a primary focus on early urinary continence recovery. We retrospectively analyzed 215 patients with large-volume BPH treated between January 2021 and December 2024. Patients were segregated into the ThuLERP group (n = 110), receiving anatomical enucleation of the middle and lateral lobes combined with vaporization cutting at the prostatic apex and anterior commissure, or the ThuLEP group (n = 105), undergoing traditional 3-lobe anatomical enucleation. Baseline characteristics, including prostate volume (102.5 ± 21.3 ml vs 104.1 ± 22.5 ml), were comparable between groups. Primary outcomes assessed continence at 1 week, 1 month, and 3 months; secondary outcomes evaluated perioperative metrics and functional recovery at 6 months. All procedures were successful. The ThuLERP group demonstrated significantly shorter total operation time (65.2 ± 18.5 minutes vs 79.4 ± 20.1 minute, P < .01) and enucleation time (48.1 ± 15.3 minutes vs 62.5 ± 17.8 minutes, P < .01) compared to ThuLEP. Safety outcomes favored ThuLERP, showing a lower incidence of postoperative hematuria requiring intervention (6.4% vs 12.4%, P < .05) and no reoperations for bleeding in the ThuLERP group compared to 1.9% in the ThuLEP group, although this difference was not statistically significant (P > .05). Notably, ThuLERP resulted in superior early continence: incontinence rates were significantly lower at 1 week (8.2% vs 21.9%, P < .01) and 1 month (2.7% vs 9.5%, P < .05). By 3 months, continence rates were comparable (> 98%). Both groups achieved similar significant improvements in International Prostate Symptom Score, quality of life, maximum urinary flow rate, and post-void residual at 6 months. Modified ThuLERP is as effective as standard ThuLEP regarding long-term functional outcomes for large-volume BPH. However, it offers distinct advantages by reducing operative time, improving hemostasis, and significantly accelerating the recovery of early urinary continence.

Indexed as

Laser TherapyProstatic HyperplasiaThuliumTransurethral Resection of ProstateAgedHumansMaleMiddle AgedPostoperative ComplicationsProstateRetrospective StudiesTreatment OutcomeUrinary IncontinenceThuliumearly urinary continence recoverylarge-volume BPHThuLEPThuLERP

Identifiers

PMID42116410
PMCPMC13166572

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.