ArticleMedicine2026
The relationship of the prognostic nutrition index with short-term prognosis in adult patients with acute myocardial infarction: A population-based study.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 authors.
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Abstract
This study aims to examine the association between the Prognostic Nutritional Index (PNI) and the short-term prognosis of adult patients experiencing acute myocardial infarction (AMI). A retrospective analysis was conducted using medical records from the MIMIC-IV database. The impact of PNI on survival outcomes was assessed using a restricted cubic spline (RCS) model. The predictive capacity of PNI was evaluated by calculating the receiver operating characteristic (ROC) curve. Kaplan-Meier (KM) analysis assessed survival rates across different PNI levels. Cox regression models were also utilized to investigate the relationship between PNI and 30-day mortality. Subgroup analyses were conducted to examine the effects of comorbidities and PNI on patient outcomes. 2347 adult patients experiencing AMI, 345 fatalities were recorded, yielding a mortality rate of 14.70%. After adjusting for potential confounders, the RCS analysis indicated a negative correlation between PNI < 43.15 and short-term mortality in these patients (P for nonlinearity < .001). The area under the ROC curve for 30-day all-cause mortality was 0.747. Concurrently, KM survival analysis demonstrated that patients with PNI < 43.15 had a poorer prognosis. Cox proportional hazards regression analysis identified PNI as an independent predictor of short-term prognosis in this patient population (HR = 0.484, 95% CI: 0.360-0.649, P < .001). Furthermore, subgroup analyses revealed significant interactions between PNI and other comorbidities regarding 30-day mortality risk (P for interaction < .05). PNI is associated with short-term mortality outcomes in patients with AMI and may serve as a valuable prognostic indicator for assessing mortality risk. retrospectively registered.
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