Evidence map›Paper›PMID 42116390›Full record

Trial reportMedicine2026

Trampoline exercise reduces anxiety and improves motor skills in children with autism spectrum disorder: A randomized controlled trial.

Bin Luo, Sawitri Wanpen, Wichai Eungpinichpong, Kurusart Konharn, Aree Rattanathongkom

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bin LuoPhysical Education, Basic Courses Division, Shandong Xiehe University, Shandong, China.ORCID 0009-0006-6802-3227
Sawitri WanpenSchool of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Wichai EungpinichpongSchool of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Kurusart KonharnSchool of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
Aree RattanathongkomDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnxiety affects approximately 40% to 50% of children with autism spectrum disorder (ASD), yet evidence-based nonpharmacological interventions remain limited. Trampoline exercise, which combines vestibular stimulation and aerobic activity, may offer dual benefits by reducing anxiety and improving motor skills in this population. To examine the effects of an 8-week trampoline exercise program on anxiety, motor performance, and physiological outcomes (heart rate variability, HRV) in children with mild-to-moderate ASD.

methodsThis assessor-blinded, randomized controlled trial (Registered at Chinese Clinical Trial Registry: ChiCTR2500104402; Date: June 17, 2025) enrolled 50 children with mild-to-moderate ASD (aged 9-14 years) from Shandong Special Education Rehabilitation Center, China. Participants were allocated 1:1 to an 8-week trampoline intervention group (IG, n = 25; 3 sessions/wk, 30 min/session) or a resistance training control group (CG, n = 25). Primary outcomes: anxiety (screen for child anxiety related disorders [SCARED] questionnaire) and HRV root mean square of successive differences (RMSSD). Secondary outcomes: standing long jump (SLJ), one-leg stance with eyes closed (OLS), and BMI (body mass index). Between-group differences were analyzed via Mann-Whitney U tests; effect sizes were reported as Cliff δ (thresholds: small = 0.11, medium = 0.28, large = 0.43).

resultsAll 50 participants completed the intervention and assessments. Compared with CG, IG showed significantly greater reductions in SCARED scores (Δ = -9.4 vs Δ = 0, false discovery rate-corrected P < .001, δ = -0.92) and improvements in HRV (RMSSD: Δ = +8.51 ms vs Δ = +1.45 ms, false discovery rate-corrected P = .003, δ = -0.66). Standing long jump (SLJ) improved markedly in IG (Δ = +15.0 cm vs CG Δ = +4.0 cm, false discovery rate-corrected P < .001, δ = -0.68). However, one-leg stance with eyes closed (OLS) showed no significant between-group difference after false discovery rate correction (Δ = +0.65 seconds vs Δ = +1.14 seconds, false discovery rate-corrected P = .076, δ = -0.37). BMI remained stable in both groups (false discovery rate-corrected P = .348).

conclusionTrampoline exercise significantly reduces anxiety and enhances lower limb explosive power in children with mild-to-moderate ASD, with effect sizes exceeding clinical thresholds. Its low cost (<$100) and high adherence (85%) support integration into school-based interventions. Future studies should explore long-term effects (3-6 months) and neural mechanisms via functional magnetic resonance imaging.

Indexed as

AnxietyAutism Spectrum DisorderExercise TherapyMotor SkillsAdolescentChildChinaFemaleHeart RateHumansMaleTreatment Outcomeanxietyautism spectrum disorderheart rate variabilitymotor skillstrampoline exercise

Identifiers

PMID42116390
PMCPMC13166828

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.