Evidence map›Paper›PMID 42116309›Full record

ArticleMedicine2026

Temporal trends in cross-country inequalities of Burkitt lymphoma burden in children under 10 years of age from 1990 to 2021.

Siqi Zhang, Tian Xia, Yu Li, Bin Pei, Ren Niu, Guoxin Huang, Xiong Wang

Abstract read
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siqi ZhangAnesthesia Room, Luzhou Maternal and Child Health Hospital (Luzhou Second People's Hospital), Luzhou, China.ORCID 0009-0005-5065-8278
Tian XiaDepartment of General Surgery, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei, China.
Yu LiDepartment of Medical Oncology, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Bin PeiCenter of Evidence-Based Medicine, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei, China.
Ren NiuAnesthesia Room, Luzhou Maternal and Child Health Hospital (Luzhou Second People's Hospital), Luzhou, China.
Guoxin HuangCenter of Evidence-Based Medicine, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, Hubei, China.
Xiong WangAnesthesia Room, Luzhou Maternal and Child Health Hospital (Luzhou Second People's Hospital), Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burkitt lymphoma (BL) is a highly aggressive form of non-Hodgkin lymphoma. Given the uncertainty surrounding the exact global incidence rate of BL, this study aims to provide a comprehensive analysis of BL epidemiology in children under 10 years of age at the global, regional, and national levels, along with a multidimensional trend analysis. This study utilizes the standardized methodology from the 2021 Burden of Disease (GBD) to describe the incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of BL in children under 10 years of age at the global, regional and national levels. The analysis includes both numerical counts and age-standardized rates (ASR) per 1,00,000 individuals, along with their 95% uncertainty intervals (UI). The burden of BL is decomposed based on population growth, aging, and epidemiological changes. Additionally, cross-national health inequalities in BL burden are quantified using standard health equity methods, and the burden of BL is projected to 2040. In 2021, there were approximately 22,878.70 (95% UI: 14,619.46-30,361.43) cases of BL in children under 10 years of age globally, with Western and Eastern Sub-Saharan Africa showing the highest incidence, prevalence, mortality and DALYs. Nigeria had the highest number of cases, with approximately 4624.35 (95% UI: 2192.40-7001.90) cases. From 1990 to 2021, the global burden of BL in children under 10 years of age showed an overall upward trend. Decomposition analysis revealed that low Socio-demographic Index (low-SDI) regions saw the most significant increase in DALYs, primarily driven by population growth. Inequality analysis indicated that countries with lower SDI continue to bear a growing burden of BL in children under 10 years of age. Notably, projections suggest that the incidence, prevalence, mortality, and DALYs for BL in children under 10 years of age will continue to rise, with global cases expected to reach 23,755 by 2040, with females exhibiting a relatively faster increase in disease burden compared with males. This study provides a comprehensive analysis of the disease burden of BL in children under 10 years of age, highlighting that regions and countries with lower SDI bear a significantly higher burden. Additionally, cross-national inequalities in BL burden have worsened over time.

Indexed as

Burkitt LymphomaChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidenceInfantMalePrevalenceQuality-Adjusted Life YearsBurkitt lymphomadisease burdenGBD 2021trends

Identifiers

PMID42116309
PMCPMC13166837

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.