Evidence map›Paper›PMID 42116303›Full record

ArticleMedicine2026

Ultrasonographic parameters comparison for pre- and postoperative carpal tunnel syndrome release: A single-center prospective study.

Kai-Xing Alvin Lee, Yu-Fang Chen, Chen-Wei Yeh, Tsung-Yu Ho, Wei-Chih Wang, Dung-Huan Liu, Pei-Ching Wu, Cheng-En Hsu, Yung-Cheng Chiu

Abstract readComparative Study
In one paragraph

Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kai-Xing Alvin LeeSchool of Medicine, China Medical University, Taichung, Taiwan.ORCID 0000-0002-4295-2064
Yu-Fang ChenDepartment of Education, China Medical University Hospital, Taichung, Taiwan.
Chen-Wei YehSchool of Medicine, China Medical University, Taichung, Taiwan.
Tsung-Yu HoSchool of Medicine, China Medical University, Taichung, Taiwan.
Wei-Chih WangDepartment of Orthopaedics Surgery, China Medical University Hsinchu Hospital, Hsinchu, Taiwan.
Dung-Huan LiuDepartment of Physical Medicine and Rehabilitation, China Medical University Hospital, Taichung, Taiwan.
Pei-Ching WuDepartment of Chinese Medicine, China Medical University Hospital, Taichung, Taiwan.
Cheng-En HsuSports Recreation and Health Management Continuing Studies-Bachelor's Degree Completion Program, Tunghai University, Taichung, Taiwan.
Yung-Cheng ChiuSchool of Medicine, China Medical University, Taichung, Taiwan.ORCID 0000-0002-6119-6444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carpal tunnel syndrome (CTS) is a prevalent condition characterized by median nerve compression, impacting a significant portion of the population worldwide. While neurophysiological testing has been traditionally employed for diagnosis, recent advancements in ultrasonography have shown promise in offering a noninvasive alternative. In this study, we aimed to evaluate the mid-term postoperative statistical changes of the median nerve and flexor retinaculum, share our ultrasonographic measurement methodologies for standardized reporting, and suggest a set of ultrasonographic parameters for postoperative tracking. A prospective cohort of 18 patients with 24 CTS-affected hands underwent comprehensive evaluations including ultrasonography, nerve conduction studies, and functional assessments before and 6 months after surgical intervention. Various ultrasonographic parameters such as cross-sectional area (CSA), bowing of the flexor retinaculum, displacement of median nerve, and flattening ratio were measured at inlet and outlet levels of the carpal tunnel. Additionally, functional outcomes including grip strength, pinch strength, disabilities of the arm, shoulder, and hand score (DASH), visual analog scale (VAS), and World Health Organization Quality of Life score (WHOQOL) were assessed. A total of 18 patients (24 wrists) with CTS were included in this study. In this study, there were 15 females and 3 males, with 12 single-sided surgeries and 6 double-sided surgeries. The mean age was 45 years old with a mean duration of symptoms of 26 months. There were no complications and no reoperations during the follow-up period. Improvements in all postoperative parameters were recorded, with statistically significant improvements noted in CSA at outlet level, bowing of the flexor retinaculum at outlet level, displacement of median nerve at inlet and outlet level, flattening ratio at the outlet level and functional scores. The primary contribution of this study lies not in individual ultrasonographic parameters but in the integration of CSA at the outlet, flexor retinaculum bowing, and median nerve displacement into a unified, clinically feasible assessment framework. This streamlined protocol is rapid, reproducible, and suitable for routine postoperative monitoring, offering greater clinical utility than single-parameter evaluation.

Indexed as

Carpal Tunnel SyndromeMedian NerveAdultAgedFemaleHand StrengthHumansMaleMiddle AgedNerve Conduction StudiesPostoperative PeriodProspective StudiesQuality of LifeTreatment OutcomeUltrasonographybowingcarpal tunnel syndromecross sectional areadisplacementflattening ratioultrasonography

Identifiers

PMID42116303
PMCPMC13166512

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.