Evidence map›Paper›PMID 42116238›Full record

ReviewEmerging infectious diseases2026

Borna Disease Virus 1 as Cause of Fatal Meningoencephalomyelitis in Wild Hedgehogs, Germany, 2022-2025.

Effrosyni Michelakaki, Benjamin Schade, Brigitte Boehm, Eva Kappe, Marcel Suchowski, Anne Kupca, Magdalena Schumacher, Anna Maria Gager, Friederike Liesche-Starnecker, Sonja Fiedler and 6 more

Abstract readReview
In one paragraph

Review in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Effrosyni Michelakaki
Benjamin Schade
Brigitte Boehm
Eva Kappe
Marcel Suchowski
Anne Kupca
Magdalena Schumacher
Anna Maria Gager
Friederike Liesche-Starnecker
Sonja Fiedler
Eva Schwarz
Zoltan Bago
Andreas Blutke
Martin Beer
Dennis Rubbenstroth
Kaspar Matiasek

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Borna disease virus 1 (BoDV-1) causes encephalitis with a fatality rate of >90% in domestic mammals and humans. Currently, the bicolored white-toothed shrew is the only known reservoir host. We report BoDV-1 infections in 15 wild European hedgehogs from an endemic area in Germany. Because hedgehogs are distant relatives of shrews and often cared for by humans, the cases raise concern regarding a potential zoonotic risk. All the hedgehogs that tested positive for BoDV-1 died of neurological disease and exhibited severe polio-predominant lymphoplasmohistiocytic meningoencephalitis. However, because of the detection of viral antigens in nonneural cells in 1 animal, we cannot completely exclude that some infected hedgehogs shed the virus. Although direct BoDV-1 transmission is known to be inefficient, our results emphasize the necessity of hygiene measures when handling hedgehogs, especially those with neurological signs who are from BoDV-1-endemic regions.

Indexed as

Borna DiseaseBorna disease virusHedgehogsMeningoencephalitisAnimalsAnimals, WildFemaleGermanyMalePhylogenyBoDV-1Borna Disease Virus 1emergingendemicErinaceus europaeusEulipotyphlaGermanyhedgehoghostinsectivorelethalmeningitis/encephalitisviruseszoonoses

Identifiers

PMID42116238
PMCPMC13174970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.