Evidence map›Paper›PMID 42116137›Full record

ArticleRespiratory research2026

Aerosol deposition in the lung as a biomarker in asthma and chronic obstruction.

Hugo Öhrneman, Andrei Malinovschi, Gui-Hong Cai, Magnus Svartengren, Hanna Nicklasson, Jonas Jakobsson, Per Wollmer, Jakob Löndahl

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hugo ÖhrnemanDivision of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, Box 118, Lund, 221 00 LUND, Sweden.
Andrei MalinovschiDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Gui-Hong CaiDepartment of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
Magnus SvartengrenDepartment of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
Hanna NicklassonDepartment of Translational Medicine, Clinical Physiology and Nuclear Medicine, Lund University, Malmö, Sweden.
Jonas JakobssonDivision of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, Box 118, Lund, 221 00 LUND, Sweden.
Per WollmerDepartment of Translational Medicine, Clinical Physiology and Nuclear Medicine, Lund University, Malmö, Sweden.
Jakob LöndahlDivision of Ergonomics and Aerosol Technology, Department of Design Sciences, Lund University, Box 118, Lund, 221 00 LUND, Sweden. jakob.londahl@design.lth.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study was to explore the potential of Airspace Dimension Assessment (AiDA) to rapidly determine the type and severity of airway obstruction, detect emphysema in individuals with chronic airflow limitation (CAL), and distinguish it from non-emphysematous obstruction, asthma, and absence of respiratory disease with normal spirometry.

methodsAmong the 744 participants measured with AiDA within the Swedish CArdioPulmonary bioImage Study (SCAPIS) cohort, 40 had asthma, and 34 had a CAL (defined by a post-bronchodilator FEV

resultsSubjects with CAL had significantly larger distal airspaces radii (median r

conclusionsThese findings display AiDA's potential in identifying emphysema as well as obstructive airway disease. The absence of an increased distal airspace radius in asthmatics confirm that r

Indexed as

Airway ObstructionAsthmaLungPulmonary Disease, Chronic ObstructivePulmonary EmphysemaAdultAerosolsAgedBiomarkersCohort StudiesFemaleForced Expiratory VolumeHumansMaleMiddle AgedSwedenAerosolsBiomarkersAerosolsAsthmaChronic airflow limitationChronic obstructive airway diseaseEmphysemaLung function

Identifiers

PMID42116137
PMCPMC13248413

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.