ArticleCytopathology : official journal of the British Society for Clinical Cytology2026
The Impact of Change in Practicing Cytopathologists' Team on Risk of Malignancy in a Retrospective Single-Centre Project of 652 Thyroid Nodules: A Quality Assurance Project.
Article in Cytopathology : official journal of the British Society for Clinical Cytology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFine needle aspiration cytology (FNAC) is a reliable, cost-effective method for evaluating thyroid lesions. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) is a standardised framework for reporting FNAC interpretations, with each category implying a risk of malignancy (ROM) and recommending evidence-based clinical management. This project aimed to (i) determine ROM rates for thyroid FNAC in a 2-year period and (ii) investigate whether a personnel change in our cytology team influenced ROM rates.
methodsWe conducted retrospective research using a pathology database for FNAC of thyroid lesions between March 2022 and February 2024. Cytohistological correlation was made in cases with histopathological follow-up and ROM was calculated for each TBSRTC category.
resultsIn a 2-year period, 652 FNAC specimens obtained from 553 patients were assessed. 28.2% (184/652) of cases had histopathological follow-up. ROM rates for each TBSRTC category were 3.6% (I), 4.9% (II), 2.9% (III), 12.5% (IV), 86.7% (V) and 100.0% (VI). After a personnel change, the distribution of TBSRTC categories shifted from categories III and IV to category II and ROM rates increased in categories II to IV. The cytohistological correlation showed limitations of FNAC interpretation in the two discrepant category II cases due to tumour subtype (diffuse sclerosing papillary thyroid carcinoma) and a retrospective lack of specimen representativeness.
conclusionsROM rates are largely consistent with published data. A personnel change in our team shifted category distribution and ROM rates, illustrating the influence of interobserver variability on diagnostic thresholds. These findings underscore the need for ongoing quality assurance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.