Evidence map›Paper›PMID 42116121›Full record

Trial reportBMC health services research2026

Partnerships and organizational capacity drive sustainability of integrated hypertension-HIV care in primary health care in Uganda.

Ambrose Byamukama, Mucunguzi Atukunda, Elizabeth Arinitwe, Brian Twinamatsiko, Andrew Mutabazi, Michael Ayebare, Winston Tindimwembwa, Alan Asiimwe, Joan Nangendo, Emmy Okello and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04624061 (Leveraging the HIV Platform for Hypertension Control in Uganda), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04624061 naunknown statusnot on this map

Leveraging the HIV Platform for Hypertension Control in Uganda

TypeinterventionalSponsorInfectious Diseases Research Collaboration, UgandaRan2020 to 2024Enrolled2,600ConditionsHIV, HypertensionArmsIntegrated HIV/HTN care model
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ambrose ByamukamaInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda. abyamukama@idrc-uganda.org.
Mucunguzi AtukundaInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Elizabeth ArinitweUganda Heart Institute (UHI), Kampala, Uganda.
Brian TwinamatsikoInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Andrew MutabaziInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Michael AyebareInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Winston TindimwembwaInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Alan AsiimweInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Joan NangendoMakerere University (MU), Kampala, Uganda.
Emmy OkelloUganda Heart Institute (UHI), Kampala, Uganda.
Gerald MutungiMinistry of Health (MoH), Kampala, Uganda.
Moses R KamyaInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Jane KabamiInfectious Diseases Research Collaboration (IDRC), Kampala, Uganda.
Edwin D CharleboisUniversity of California San Francisco (UCSF), San Francisco, USA.

Funding

European and Developing Countries Clinical Trials Partnership (EDCTP) CSA2018HS-2518
6 · The paper itself

Abstract

backgroundThe co-occurrence of HIV and non-communicable diseases (NCDs), particularly hypertension, is a growing global health issue. As people living with HIV (PLHIV) live longer due to antiretroviral therapy (ART), they become more susceptible to NCDs like hypertension due to chronic inflammation, long-term drug side effects, and metabolic factors that compound their risk. The integrated HIV/HTN project implemented a feasible and cost-effective multi-component intervention in several public health facilities in Uganda. In this study, we sought to evaluate the program sustainability of the intervention by the public health delivery system.

methodsA mixed-methods cross-sectional study was conducted across 26 public health facilities in 13 intervention districts of southwestern Uganda. Quantitative data were collected using the Program Sustainability Assessment Tool (PSAT) from District Health Officers (N = 15), HIV focal persons (N = 10), and Facility/Clinic in-charges (N = 25). Qualitative data were gathered through in-depth interviews with healthcare managers and analyzed using Stata and Dedoose software.

resultsThe PSAT Partnerships domain scored high (5.68), reflecting strong stakeholder engagement, communication, and leadership involvement. The Organizational Capacity domain also performed well (5.66), with strong integration of hypertension screening and data management, resource management and staff training rated at 4.24 and 4.9 respectively. Integration of HTN into HIV Care Evaluation scored (5.54), excelling in public communication but needing improvement in reporting and evaluation capacity. The Communications domain (5.51) showed moderate effectiveness, with room to enhance public engagement and feedback strategies. Environmental Support was the weakest domain (4.73), highlighting the need for better resource mobilization and training adequacy.

conclusionThe sustainability of a multi-component care model was strongly influenced by strong partnerships and leadership. To ensure long-term success, environmental support, resource management, and sustainability planning is essential. Addressing these gaps will strengthen ongoing integration efforts in resource-limited settings. REGISTRY: ClinicalTrials.gov, TRN: NCT04624061, Registration date: 04 November 2022.

Indexed as

Capacity BuildingDelivery of Health Care, IntegratedHIV InfectionsHypertensionPrimary Health CareCross-Sectional StudiesHumansProgram EvaluationPublic Health InfrastructureUgandaHIVHypertensionIntegrationProgram sustainability assessment

Identifiers

PMID42116121
PMCPMC13339695

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.