ArticleBMC ophthalmology2026
Retinal and choroidal changes in young adults during near work and eye closure measured by wide-field OCTA.
Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Short-Term Effects of Optically Induced and Digitally Simulated Myopic Blur on Retinal Perfusion: Insights From Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundMyopia is a major global public health concern, and near work has been identified as a key risk factor for its onset and progression. This study aimed to evaluate short-term retinal and choroidal vascular and structural responses to near work and subsequent eye-closure rest in young adults.
methodsThirty medical students (aged 18-24 years) underwent wide-field swept-source OCTA at baseline, after 20, 40, and 60 min of near work, and after 10, 20, and 30 min of eye-closure rest. Vascular parameters of the nerve fiber layer vascular plexus (NFLVP), superficial vascular complex (SVC), deep vascular complex (DVC), choriocapillaris, and choroid were analyzed.
resultsDuring near work, NFLVP vessel density (VD) and vessel diameter index increased in the temporal 1-3 mm and 6-9 mm sectors; the 6-9 mm temporal sector remained elevated above baseline throughout rest (all p < 0.05). SVC VD, small vessel density, and vessel length density in the superior 3-6 mm sector fell below baseline during rest (all p < 0.05). Choroidal perfusion area, thickness, and stromal volume declined significantly relative to pre-rest values at 20 min of rest (all p < 0.05).
conclusionsNFLVP perfusion in the temporal 6-9 mm sector increased during near work and remained elevated above baseline throughout the rest period; SVC perfusion in the same sector likewise remained above baseline during rest, while SVC perfusion in the superior 3-6 mm sector fell below baseline. These alterations may provide important insights into the vascular regulatory mechanisms underlying myopia development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.