Evidence map›Paper›PMID 42115977›Full record

ArticleBMC medical imaging2026

Styloid process morphology in extracranial internal carotid artery dissection: a CTA case-control study.

Xueke Zhang, Xin Shen, Shaokun Hu, Yiru Shen, Zeyuan Cao, Yuanyuan Wu, Dongliang Hu, Manman Cui, Duchang Zhai, Dai Shi and 2 more

Abstract read
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Article in BMC medical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Xueke Zhang *Department of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Xin Shen *Department of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Shaokun HuDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Yiru ShenSuzhou Medical College of Soochow University, 199 Ren'ai Road, Huqiu District, Suzhou, Jiangsu, 215026, China.
Zeyuan CaoDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Yuanyuan WuDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Dongliang HuDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Manman CuiDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Duchang ZhaiDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China.
Dai ShiDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China. shidai318@163.com.
Wu CaiDepartment of Radiology, The Second Affiliated Hospital of Soochow University, San Xiang Road No. 1055, Suzhou, Jiangsu, 215004, China. xwg608@126.com.
Shenghong JuDepartment of Radiology, Zhongda Hospital, Medical School of Southeast University, Ding Jia Qiao Road No. 87, Nanjing, Jiangsu, 210009, China.

Funding

"National Tutor System" Training Program for Health Youth Key Talents in Suzhou Qngg2021006Scientific Research Project of Jiangsu Provincial Health Commission M2024102Suzhou Clinical Key Disease Diagnosis and Treatment Technology Special Project LCZX202309the Project of State Key Laboratory of Radiation Medicine and Protection, Soochow University GZK12024025the Project of State Key Laboratory of Radiation Medicine and Protection, Soochow University GZK12024051the Subject Construction Support Project of the Second Affiliated Hospital of Soochow University XKTJ-HTD2025003
6 · The paper itself

Abstract

backgroundTo evaluate the association between styloid process (SP) morphology derived from CTA and extracranial internal carotid artery dissection (ICAD). MATERIALS AND

methodsThis retrospective case-control study included 85 patients with unilateral extracranial ICAD and 85 frequency-matched controls who underwent head and neck CTA. Two neuroradiologists independently measured SP length, the distance from the SP tip to the internal carotid artery (SPT-ICA distance), and SP orientation (medial and anterior inclination angles). Group comparisons were performed between the dissection side in the ICAD group and the corresponding matched side in controls. Multivariable logistic regression was used to identify independent morphologic factors associated with ICAD, and ROC analysis was performed to evaluate the diagnostic performance of each individual parameter and of the combined model.

resultsCompared with controls, ICAD showed a longer SP, a shorter SPT-ICA distance, and a smaller anterior inclination angle (all p < 0.001). Multivariable logistic regression identified SP length, SPT-ICA distance, and anterior inclination angle as independent factors associated with ICAD. ROC analysis showed that the combined model achieved the best performance (AUC = 0.836), compared with SP length (AUC = 0.752), SPT-ICA distance (AUC = 0.742), and anterior inclination angle (AUC = 0.717).

conclusionThe combined model based on SP length, SPT-ICA distance, and anterior inclination angle showed the best performance, suggesting that these CTA-derived SP morphologic features may help identify an anatomic pattern associated with extracranial ICAD.

Indexed as

Carotid Artery, Internal, DissectionComputed Tomography AngiographyTemporal BoneAdultAgedCarotid Artery, InternalCase-Control StudiesFemaleHumansMaleMiddle AgedRetrospective StudiesROC CurveCTAEagle syndromeInternal carotid artery dissectionStyloid process

Identifiers

PMID42115977
PMCPMC13330466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.